دورية أكاديمية

Potential Strategies to Improve the Effectiveness of Drug Therapy by Changing Factors Related to Tumor Microenvironment.

التفاصيل البيبلوغرافية
العنوان: Potential Strategies to Improve the Effectiveness of Drug Therapy by Changing Factors Related to Tumor Microenvironment.
المؤلفون: Cao D; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Naiyila X; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Li J; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Huang Y; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Chen Z; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Chen B; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Li J; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Guo J; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Dong Q; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Ai J; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Yang L; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Liu L; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China., Wei Q; Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Aug 10; Vol. 9, pp. 705280. Date of Electronic Publication: 2021 Aug 10 (Print Publication: 2021).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne : Frontiers Media S.A., [2013]-
مستخلص: A tumor microenvironment (TME) is composed of various cell types and extracellular components. It contains tumor cells and is nourished by a network of blood vessels. The TME not only plays a significant role in the occurrence, development, and metastasis of tumors but also has a far-reaching impact on the effect of therapeutics. Continuous interaction between tumor cells and the environment, which is mediated by their environment, may lead to drug resistance. In this review, we focus on the key cellular components of the TME and the potential strategies to improve the effectiveness of drug therapy by changing their related factors.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2021 Cao, Naiyila, Li, Huang, Chen, Chen, Li, Guo, Dong, Ai, Yang, Liu and Wei.)
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فهرسة مساهمة: Keywords: cancer-associated fibroblasts; drug therapy; targeted therapy; tumor microenvironment; tumor-associated macrophages
تواريخ الأحداث: Date Created: 20210827 Latest Revision: 20210828
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8383319
DOI: 10.3389/fcell.2021.705280
PMID: 34447750
قاعدة البيانات: MEDLINE
الوصف
تدمد:2296-634X
DOI:10.3389/fcell.2021.705280