دورية أكاديمية
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019.
| العنوان: | Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
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| المؤلفون: | Fraiha ALS; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Matos ACD; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Cunha JLR; Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Santos BSÁDS; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.; Laboratório de Imunologia de Doenças Virais, Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil., Peixoto MVC; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Oliveira AGG; Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Galinari GCF; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Nascimento HIJ; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Guedes MIMC; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Machado AMV; Laboratório de Imunologia de Doenças Virais, Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil., Costa EA; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil., Lobato ZIP; Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil. ziplobato@gmail.com. |
| المصدر: | Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2021 Dec; Vol. 52 (4), pp. 2421-2430. Date of Electronic Publication: 2021 Aug 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer International Publishing Country of Publication: Brazil NLM ID: 101095924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4405 (Electronic) Linking ISSN: 15178382 NLM ISO Abbreviation: Braz J Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2019- : Switzerland, AG : Springer International Publishing Original Publication: Rio de Janeiro, RJ, Brasil : Sociedade Brasileira de Microbiologia |
| مواضيع طبية MeSH: | Influenza A Virus, H1N1 Subtype*/genetics , Influenza A Virus, H3N2 Subtype*/genetics , Orthomyxoviridae Infections*/veterinary , Orthomyxoviridae Infections*/virology , Swine Diseases*/epidemiology, Animals ; Brazil ; Swine |
| مستخلص: | The swine influenza A virus (SIAV) subtypes/lineages H1N1pdm09, H3N2, H1N2, and H1N1 of seasonal human origin are widespread in Brazilian swine herds. A monovalent inactivated H1N1pdm09 vaccine was licensed in Brazil in 2014. However, there are concerns about its efficacy due to the limited vaccine cross-protection against heterologous viruses and the potential for exacerbated reactions against vaccine strains. Thus, monitoring SIAVs subtypes/lineages that are circulating in the Brazilian swine population is important, by applying a fast and efficient diagnostic test in herd field samples. A RT-PCR assay was developed, using primers specific for HA subtyping of Brazilian SIAV, and was used to evaluate the occurrence of subtypes from samples collected between 2012 and 2019. From 167 field samples positive for influenza A, 117 were subtyped by nested RT-PCR assay. A higher occurrence of H1N1pdm was observed from 2012 to 2015, H3N2 in 2017, and H1hu in 2017 to 2019. A hemagglutination inhibition test was performed in serum samples received from 2017 to 2019, confirming these data. The molecular data highlights the importance of H1hu and H3N2 detection since there are no vaccines available for the subtypes/lineages and raises an alert of H1hu for its potential to infect humans. Serological data suggest a cyclical profile of occurrence between the H3N2 and H1N1pdm over time. Monitoring SIAVs circulating in Brazilian swine herds is necessary, which provides the relevant information for field veterinarians to apply effective control measures on the properties. (© 2021. Sociedade Brasileira de Microbiologia.) |
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| فهرسة مساهمة: | Keywords: Brazil; Genotyping; H1N1pdm; H1hu; H3N2; Influenza virus; Serology; Swine |
| تواريخ الأحداث: | Date Created: 20210829 Date Completed: 20211229 Latest Revision: 20211229 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8402972 |
| DOI: | 10.1007/s42770-021-00550-y |
| PMID: | 34455547 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1678-4405 |
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| DOI: | 10.1007/s42770-021-00550-y |