تقرير
أعرض في EDS

Case Report: SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.

التفاصيل البيبلوغرافية
العنوان: Case Report: SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.
المؤلفون: Marinho PS; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., da Cunha AJLA; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Department of Pediatrics, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Chimelli L; Laboratory of Neuropathology, Rio de Janeiro State Brain Institute, Rio de Janeiro, Brazil., Avvad-Portari E; Department of Pathological Anatomy, Fernandes Figueira Institute, Fiocruz, Rio de Janeiro, Brazil.; School of Medicine, State University of Rio de Janeiro, Rio de Janeiro, Brazil., Andreiuolo FDM; Laboratory of Neuropathology, Rio de Janeiro State Brain Institute, Rio de Janeiro, Brazil., de Oliveira-Szejnfeld PS; Diagnostic Imaging Department, Escola Paulista de Medicina, School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.; Diagnostic Imaging Department, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Mendes MA; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Gomes IC; Genetics Department, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Anatomic Pathology Service, Jesus Municipal Hospital, Rio de Janeiro, Brazil., Souza LRQ; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Guimarães MZ; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.; Department of Phamacology, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Goldman SM; Diagnostic Imaging Department, Escola Paulista de Medicina, School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil., de Oliveira MBG; Department of Pediatrics, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Rehen S; Diagnostic Imaging Department, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Amim J Jr; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Tovar-Moll F; Diagnostic Imaging Department, Escola Paulista de Medicina, School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.; Diagnostic Imaging Department, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Prata-Barbosa A; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Department of Pediatrics, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
المصدر: Frontiers in medicine [Front Med (Lausanne)] 2021 Aug 16; Vol. 8, pp. 677001. Date of Electronic Publication: 2021 Aug 16 (Print Publication: 2021).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne, Switzerland : Frontiers Media S.A., [2014]-
مستخلص: SARS-CoV-2 infection during pregnancy is not usually associated with significant adverse effects. However, in this study, we report a fetal death associated with mild COVID-19 in a 34-week-pregnant woman. The virus was detected in the placenta and in an unprecedented way in several fetal tissues. Placental abnormalities (MRI and anatomopathological study) were consistent with intense vascular malperfusion, probably the cause of fetal death. Lung histopathology also showed signs of inflammation, which could have been a contributory factor. Monitoring inflammatory response and coagulation in high-risk pregnant women with COVID-19 may prevent unfavorable outcomes, as shown in this case.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2021 Marinho, da Cunha, Chimelli, Avvad-Portari, Andreiuolo, de Oliveira-Szejnfeld, Mendes, Gomes, Souza, Guimarães, Goldman, de Oliveira, Rehen, Amim, Tovar-Moll and Prata-Barbosa.)
References: PLoS One. 2020 Apr 16;15(4):e0230295. (PMID: 32298273)
Am J Clin Pathol. 2020 Jun 8;154(1):23-32. (PMID: 32441303)
Nat Commun. 2020 Oct 12;11(1):5128. (PMID: 33046695)
BMC Med. 2020 Oct 19;18(1):330. (PMID: 33070775)
J Obstet Gynaecol Res. 2007 Aug;33(4):423-30. (PMID: 17688607)
MMWR Morb Mortal Wkly Rep. 2020 Sep 25;69(38):1347-1354. (PMID: 32970655)
Histopathology. 2020 Dec;77(6):994-999. (PMID: 32692408)
J Microbiol Immunol Infect. 2021 Feb;54(1):69-76. (PMID: 32847748)
BMJ. 2020 Jun 8;369:m2107. (PMID: 32513659)
J Perinat Med. 2020 Nov 26;48(9):900-911. (PMID: 33001856)
Case Rep Womens Health. 2021 Apr;30:e00289. (PMID: 33527073)
Lancet. 2020 Mar 7;395(10226):809-815. (PMID: 32151335)
J Clin Med. 2020 Oct 26;9(11):. (PMID: 33114779)
Nat Microbiol. 2020 Oct;5(10):1299-1305. (PMID: 32651556)
JAMA. 2020 May 12;323(18):1846-1848. (PMID: 32215581)
Eur J Obstet Gynecol Reprod Biol. 2021 Feb;257:11-18. (PMID: 33310656)
Am J Obstet Gynecol. 2021 Apr;224(4):382.e1-382.e18. (PMID: 33091406)
Case Rep Womens Health. 2020 Jul 12;27:e00243. (PMID: 32704477)
J Thromb Haemost. 2020 Nov;18(11):3086-3098. (PMID: 32846051)
Nat Commun. 2020 Jul 14;11(1):3572. (PMID: 32665677)
J Thromb Thrombolysis. 2020 May;49(4):618-629. (PMID: 32248336)
Am J Perinatol. 2020 Jun;37(8):861-865. (PMID: 32305046)
BMC Pregnancy Childbirth. 2021 Feb 5;21(1):108. (PMID: 33546624)
Ultrasound Obstet Gynecol. 2021 Feb;57(2):242-247. (PMID: 32798244)
Vasc Health Risk Manag. 2020 Nov 13;16:455-462. (PMID: 33223833)
J Perinat Med. 2020 Nov 26;48(9):950-958. (PMID: 32975205)
Front Cell Dev Biol. 2020 Aug 19;8:783. (PMID: 32974340)
JAMA Pediatr. 2021 Feb 1;175(2):157-167. (PMID: 33044493)
Am J Reprod Immunol. 2020 Nov;84(5):e13320. (PMID: 32779790)
Pediatr Infect Dis J. 2020 Sep;39(9):e257-e260. (PMID: 32658096)
Obstet Gynecol. 2020 Nov;136(5):1016-1020. (PMID: 32649505)
Hum Reprod. 2021 Mar 18;36(4):899-906. (PMID: 33346816)
فهرسة مساهمة: Keywords: COVID-19; SARS-CoV-2; fetal death; mother-to-child transmission; placental thromboembolism; pregnancy
تواريخ الأحداث: Date Created: 20210906 Latest Revision: 20210907
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8415358
DOI: 10.3389/fmed.2021.677001
PMID: 34485327
قاعدة البيانات: MEDLINE
الوصف
تدمد:2296-858X
DOI:10.3389/fmed.2021.677001