التفاصيل البيبلوغرافية
| العنوان: |
Visualization of Both the Superficial and Deep Lymphatic System of the Upper Extremity Using Magnetic Resonance Lymphography. |
| المؤلفون: |
Wolfs JAGN; Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Qiu SS; Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Lobbes MBI; Department of Medical Imaging, Zuyderland Medical Center, Geleen, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands., Bijkerk E; Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., van der Hulst RRWJ; Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Keuter XHA; Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht, The Netherlands. |
| المصدر: |
Lymphatic research and biology [Lymphat Res Biol] 2022 Jun; Vol. 20 (3), pp. 275-281. Date of Electronic Publication: 2021 Sep 02. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101163587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8585 (Electronic) Linking ISSN: 15396851 NLM ISO Abbreviation: Lymphat Res Biol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Larchmont, NY : Mary Ann Liebert, Inc., c2003- |
| مواضيع طبية MeSH: |
Lymphatic Vessels*/diagnostic imaging , Lymphatic Vessels*/pathology , Lymphedema*/diagnostic imaging , Lymphedema*/pathology, Contrast Media ; Humans ; Lymphatic System/diagnostic imaging ; Lymphatic System/pathology ; Lymphography/methods ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Spectroscopy ; Upper Extremity/pathology |
| مستخلص: |
Background: The lymphatic system consists of the superficial and deep lymphatic system. Several diagnostic methods are used to assess the lymphatic system. Lymphoscintigraphy and indocyanine green lymphography are widely applied, both showing disadvantages, such as a poor resolution and lack of field of view. Magnetic resonance lymphography (MRL) shows satisfactory temporal and spatial resolution. The aim of this study was to assess both the superficial and deep lymphatic system in the upper extremity of healthy subjects, using an MRL protocol. Methods and Results: Ten healthy volunteers underwent an MRL examination, using a three Tesla MRI unit. Water-soluble gadolinium was used as a contrast agent. MRL images were evaluated by an experienced radiologist on image quality, enhancement of veins and lymphatic vessels, and characteristics of the latter. Overall image quality was good to excellent. In all subjects, veins and lymphatic vessels could be distinguished. Superficial and deep lymphatic vessels were seen in 9 out of 10 subjects. Lymphatic vessels with a diameter between 0.9 and 4.3 mm were measured. Both veins and lymphatic vessels showed their characteristic appearance. Enhancement of veins was seen directly after contrast agent injection, which decreased over time. Lymphatic vessel enhancement slowly increased over time. Mean total MRL examination (room) time was 110 minutes (81 minutes scan time). Conclusions: The MRL protocol accurately visualizes both deep and superficial lymphatic vessels showing their characteristic appearances with high spatial resolution, indicating the MRL can be of value in diagnosing and staging peripheral lymphedema. |
| فهرسة مساهمة: |
Keywords: lymphatic system; lymphedema; magnetic resonance lymphography; upper extremity |
| المشرفين على المادة: |
0 (Contrast Media) |
| تواريخ الأحداث: |
Date Created: 20210907 Date Completed: 20220614 Latest Revision: 20220623 |
| رمز التحديث: |
20221213 |
| DOI: |
10.1089/lrb.2021.0012 |
| PMID: |
34491853 |
| قاعدة البيانات: |
MEDLINE |
