دورية أكاديمية
Anti-inflammatory and antioxidant activities of chemical constituents from the flower buds of Buddleja officinalis .
| العنوان: | Anti-inflammatory and antioxidant activities of chemical constituents from the flower buds of Buddleja officinalis . |
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| المؤلفون: | Huang FB; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Liang N; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Hussain N; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; Department of Chemistry, University of Baltistan Skardu, Skardu, Pakistan., Zhou XD; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Ismail M; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; Department of Chemistry, Karakoram International University, Gilgit, Pakistan., Xie QL; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Yu HH; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Jian YQ; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Peng CY; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Li B; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Liu B; Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, China., Chen SH; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China., Peng QH; Hunan Provincial Key Laboratory for the Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China., Wang W; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China. |
| المصدر: | Natural product research [Nat Prod Res] 2022 Jun; Vol. 36 (12), pp. 3031-3042. Date of Electronic Publication: 2021 Sep 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Buddleja*/chemistry, Anti-Inflammatory Agents/chemistry ; Antioxidants/chemistry ; Flowers/chemistry ; Lipopolysaccharides/pharmacology ; Plant Extracts/chemistry ; Tumor Necrosis Factor-alpha |
| مستخلص: | Five new glycosides including mimenghuasu A and B ( 1 - 2 ), isolinarin ( 3 ), cyclocitralosides A and B ( 4-5 ), along with forty-seven known compounds were isolated from the flower buds of Buddleja officinalis . These structures were elucidated by extensive spectroscopic analysis (UV, IR, 1 D, 2 D NMR, and MS spectra). The anti-inflammatory activities of the isolated compounds were determined by enzyme-linked immunosorbent assay (ELISA) on the expression of TNF- α (LPS-activated RAW264.7 cells) and MTT experiment on LPS-induced HUVECs proliferation effects. Good suppressive effects on the expression of TNF- α were shown by 4 and 5 with IC |
| فهرسة مساهمة: | Keywords: Buddleja officinalis; Scrophulariaceae; anti-inflammatory; anti-oxidation; chemical constituents; glycosides; mimenghua |
| المشرفين على المادة: | 0 (Anti-Inflammatory Agents) 0 (Antioxidants) 0 (Lipopolysaccharides) 0 (Plant Extracts) 0 (Tumor Necrosis Factor-alpha) |
| تواريخ الأحداث: | Date Created: 20210909 Date Completed: 20220623 Latest Revision: 20220623 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/14786419.2021.1952577 |
| PMID: | 34498975 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2021.1952577 |