دورية أكاديمية
أعرض في EDS

Early detection of macrovascular complications in type 2 diabetes mellitus in Medan, North Sumatera, Indonesia: A cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: Early detection of macrovascular complications in type 2 diabetes mellitus in Medan, North Sumatera, Indonesia: A cross-sectional study.
المؤلفون: Amelia R; 1Department of Community Medicine/Public Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia., Harahap J; 1Department of Community Medicine/Public Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia., Yunanda Y; 1Department of Community Medicine/Public Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia., Wijaya H; Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia., Fujiati II; 1Department of Community Medicine/Public Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia., Yamamoto Z; Department of Histology, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, 20155, Indonesia.
المصدر: F1000Research [F1000Res] 2021 Aug 16; Vol. 10, pp. 808. Date of Electronic Publication: 2021 Aug 16 (Print Publication: 2021).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: F1000 Research Ltd Country of Publication: England NLM ID: 101594320 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-1402 (Electronic) Linking ISSN: 20461402 NLM ISO Abbreviation: F1000Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : F1000 Research Ltd
مواضيع طبية MeSH: Atrial Fibrillation* , Diabetes Mellitus, Type 2*/complications, Cross-Sectional Studies ; Humans ; Indonesia/epidemiology ; Quality of Life
مستخلص: Background: Macrovascular complications occur very frequently in patients with type 2 diabetes mellitus (T2DM) with a high mortality rate, due to the development of cardiovascular disease (CVD), such as stroke, atherosclerosis acceleration, and atrial fibrillation. T2DM is a significant risk factor for CVD and has become the leading cause of death. The purpose of this study was to detect the early risk of macrovascular complications by using the ankle brachial index (ABI) as a marker. Methods: This study was an analytic study with a cross-sectional approach. The study population was patients with T2DM from several primary health care centers in Medan. In total, 89 subjects who met the inclusion and exclusion criteria were recruited with consecutive sampling. ABI was determined as the ratio of systolic blood pressure in the brachial artery to the posterior tibial artery after the subjects had been relaxed and felt comfortable in a supine position. Examination of vitamin D and lipid profile was derived from examination of venous blood.  Data were processed using SPSS and analyzed with one-way ANOVA. Results: The study found that there was a relationship between LDL-C, triglyceride, and vitamin D (25OH-D) based on the ABI (p > 0.05). Conclusions: ABI can be used for an early detection of macrovascular complications. Apart from being easy to perform, ABI was non-invasive. Some other risk factors that can also be used to assess complications and have relationships with ABI were LDL-C, triglyceride, and vitamin D (25OH-D). Complications in T2DM patients can be prevented with reasonable blood sugar control and lifestyle changes. Education and motivation need to be given to patients so that they become more independent in controlling their disease and improving their quality of life.
Competing Interests: No competing interests were disclosed.
(Copyright: © 2021 Amelia R et al.)
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فهرسة مساهمة: Keywords: HDL-C; LDL-C; ankle brachial index; hydroxy vitamin D; macrovascular complications; triglyceride
سلسلة جزيئية: figshare 10.6084/m9.figshare.14915724.v1
تواريخ الأحداث: Date Created: 20210916 Date Completed: 20211025 Latest Revision: 20211025
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8411276
DOI: 10.12688/f1000research.54649.1
PMID: 34527220
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-1402
DOI:10.12688/f1000research.54649.1