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The role of forskolin as a lipolytic stimulator during in vitro oocyte maturation and the in vitro embryo production of livestock.

التفاصيل البيبلوغرافية
العنوان: The role of forskolin as a lipolytic stimulator during in vitro oocyte maturation and the in vitro embryo production of livestock.
المؤلفون: Raza SHA; College of Animal Science and Technology, Northwest A&F University, Yangling, China.; National Beef Cattle Improvement Center, Northwest A&F University, Yangling, China., Abd El-Aziz AH; Animal Husbandry and Animal Wealth Development Department, Faculty of Veterinary Medicine, Daman Hour University, Damanhour, Egypt., Abdelnour SA; Animal Production Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt., Easa AA; Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Damanhour, Egypt., Alagawany M; Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, Egypt., Farag MR; Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt., Al-Mutary MG; Department of Basic Sciences, College of Education, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Elfadadny A; Department of Animal Medicine, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt., Khan R; Department of Livestock Management, Breeding and Genetics, The University of Agriculture Peshawar, Peshawar, Pakistan., Quan G; Yunnan Animal Science and Veterinary Institute, Kunming, China., Cheng G; College of Animal Science and Technology, Northwest A&F University, Yangling, China., Zan L; College of Animal Science and Technology, Northwest A&F University, Yangling, China.; National Beef Cattle Improvement Center, Northwest A&F University, Yangling, China.
المصدر: Reproduction in domestic animals = Zuchthygiene [Reprod Domest Anim] 2021 Dec; Vol. 56 (12), pp. 1486-1496. Date of Electronic Publication: 2021 Oct 14.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Paul Parey Scientific Publishers Country of Publication: Germany NLM ID: 9015668 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0531 (Electronic) Linking ISSN: 09366768 NLM ISO Abbreviation: Reprod Domest Anim Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin ; Hamburg : Paul Parey Scientific Publishers, c1990-
مواضيع طبية MeSH: In Vitro Oocyte Maturation Techniques*/veterinary , Livestock*, Animals ; Colforsin/pharmacology ; Cryopreservation/veterinary ; Fertilization in Vitro/veterinary ; Oocytes
مستخلص: Cryopreservation is a modern technique which assists in the preservation of genetic material from oocytes and embryos for a long time. However, elevated vulnerability to cryopreservation due to the large accumulation of intracellular lipids within oocytes or embryos avoids success of this method. These lipids remain the main crucial factor limiting survival rates of oocytes and embryos after thawing. Lipid ingathering in the oocyte cytoplasm augments lipid peroxidation (LPO) and oxidative stress increases the apoptosis process, declines the viability after thawing, declines cytoskeleton actin filament injuries, lowers the blastocyst rates and reduces cryotolerance in the early stages of embryo development. There have been several attempts to reduce the ingathering of intracellular lipids in oocytes or embryos during the cryopreservation process, in that way enhancing the competence of cryopreserved oocytes or embryos and increasing their viability. One of the most applied agents for chemical delipidation is forskolin. Forskolin exhibited a possible part in improving the oocytes cryopreservation through stimulating cyclic adenosine monophosphate (cAMP) production. The main purpose of cAMP modulation is to provide energy to sustain the mammalian oocytes´ meiotic arrest. The purpose of the existing article is to assess and offer more evidence concerning the forskolin utilization as a modulator of cAMP during the cryopreservation of oocytes and its influence on meiosis completion and the reorganization of cytoplasm, which are prerequisites for the development of oocytes in addition to the contribution to fertilization and subsequently, the development of embryos.
(© 2021 Wiley-VCH GmbH.)
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معلومات مُعتمدة: 2018YFD0501700 National Key Research and Development Program of China; 2020T130540 China Postdoctoral Science Foundation; CARS-37 National Beef and Yak Industrial Technology System; NYKJ-2018-LY09 Agricultural Science and Technology Innovation and Transformation Project of Shaanxi Province; 2016KTCL02-15 Technical Innovation Engineering Project of Shaanxi Province
فهرسة مساهمة: Keywords: embryo; forskolin; in vitro; lipolytic; oocytes
المشرفين على المادة: 1F7A44V6OU (Colforsin)
تواريخ الأحداث: Date Created: 20210930 Date Completed: 20220117 Latest Revision: 20220117
رمز التحديث: 20221213
DOI: 10.1111/rda.14021
PMID: 34592022
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-0531
DOI:10.1111/rda.14021