دورية أكاديمية
Development of synthetic antigen vaccines for COVID-19.
العنوان: | Development of synthetic antigen vaccines for COVID-19. |
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المؤلفون: | Viana Invenção MDC; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil., Melo ARDS; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil., de Macêdo LS; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil., da Costa Neves TSP; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil., de Melo CML; Laboratory of Immunological and Antitumor Analysis, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil., Cordeiro MN; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil., de Aragão Batista MV; Laboratory of Molecular Genetics and Biotechnology, Department of Biology, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., de Freitas AC; Laboratory of Molecular Studies and Experimental Therapy - LEMTE, Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil. |
المصدر: | Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2021 Nov 02; Vol. 17 (11), pp. 3855-3870. Date of Electronic Publication: 2021 Oct 06. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2015- : Philadelphia, PA : Taylor & Francis Original Publication: Austin, Tex. : Landes Bioscience |
مواضيع طبية MeSH: | COVID-19*, COVID-19 Vaccines ; Humans ; Pandemics ; SARS-CoV-2 ; Vaccines, Synthetic/genetics |
مستخلص: | The current pandemic called COVID-19 caused by the SARS-CoV-2 virus brought the need for the search for fast alternatives to both control and fight the SARS-CoV-2 infection. Therefore, a race for a vaccine against COVID-19 took place, and some vaccines have been approved for emergency use in several countries in a record time. Ongoing prophylactic research has sought faster, safer, and precise alternatives by redirecting knowledge of other vaccines, and/or the development of new strategies using available tools, mainly in the areas of genomics and bioinformatics. The current review highlights the development of synthetic antigen vaccines, focusing on the usage of bioinformatics tools for the selection and construction of antigens on the different vaccine constructions under development, as well as strategies to optimize vaccines for COVID-19. |
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فهرسة مساهمة: | Keywords: SARS-CoV-2; adjuvants; immunoinformatics; in silico; nucleic acid vaccines |
المشرفين على المادة: | 0 (COVID-19 Vaccines) 0 (Vaccines, Synthetic) |
تواريخ الأحداث: | Date Created: 20211006 Date Completed: 20220114 Latest Revision: 20231105 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC8506811 |
DOI: | 10.1080/21645515.2021.1974288 |
PMID: | 34613880 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2164-554X |
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DOI: | 10.1080/21645515.2021.1974288 |