دورية أكاديمية
أعرض في EDS

Clear Cell Odontogenic Carcinoma a Systematic Review.

التفاصيل البيبلوغرافية
العنوان: Clear Cell Odontogenic Carcinoma a Systematic Review.
المؤلفون: Labrador AJP; av 5 de diciembre, 3303, Acarigua Portuguesa, Venezuela. ajpl26@yahoo.com., Marin NRG; Department of Otolaryngologist Military Hospital, Bogota, Colombia., Valdez LHM; Las Golondrinas Mz. B lote 9. Los Olivos, Lima, Peru., Valentina MP; Universidad de Cuenca Facultad de Odontologia, Cuenca, Ecuador., Sanchez KBT; Av. El Olivar 3879 San Martin de Porres, Lima, Peru., Ibazetta KAR; Av. Pablo Carriquiry 705 San Isidro, Lima, Peru., Johan B; All Medical Group, Bogota, Colombia., Cesar AV; Universidad Señor de SIPAN Dental School, Chiclayo, Peru., Wright JM; Department of Diagnostic Sciences, Texas A&M University College of Dentistry, 3302, Gaston Ave, Dallas, TX, 75246, USA.
المصدر: Head and neck pathology [Head Neck Pathol] 2022 Sep; Vol. 16 (3), pp. 838-848. Date of Electronic Publication: 2021 Oct 07.
نوع المنشور: Journal Article; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Country of Publication: United States NLM ID: 101304010 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-0568 (Electronic) Linking ISSN: 1936055X NLM ISO Abbreviation: Head Neck Pathol Subsets: MEDLINE
أسماء مطبوعة: Publication: June 2011- : New York : Springer Science+ Business Media
Original Publication: Secaucus, NJ : Humana Press
مواضيع طبية MeSH: Carcinoma* , Mouth Neoplasms* , Odontogenic Tumors*, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Mandible ; Middle Aged ; Retrospective Studies ; Young Adult
مستخلص: Clear cell Odontogenic Carcinoma (CCOC) is an uncommon malignant odontogenic tumor (MOT). It is the fifth most common MOT. A systematic review is presented of reported cases, case series and retrospective studies of CCOC, to determine trends in presentation, diagnostic features, treatment, and patient outcome. Searches of detailed databases were carried out to identify papers reporting CCOC. The variables were demographics, patient symptoms, tumor location, histopathological findings, immunohistochemical studies, treatment, follow-up, and recurrence. 117 cases were identified; CCOC was most frequently seen in mature females 65% (n = 76). The total average age was 55.4 with a range from 17 to 89 years, for females 56.4 and males 53.6 years. The mean size was 3.41 cm. The most common location was in the mandibular body 36.2% (n = 42), followed by the anterior mandible 23.3% (n = 27). The most common clinical presentation was a swelling 80.4% (n = 74), and the main symptom was pain 41.3% (n = 31), followed by painless lesion 24% (n = 18). The most common Immunohistochemistry positive expression was CK19, EMA, and CEA, and for special staining periodic acid Shiff (PAS); 97% of cases were treated surgically. The average follow-up was 30.3 months, and recurrence was reported in 52.4% of the cases. Conclusion: CCOC shows a strong predilection for the body and anterior mandible, and females are more frequently affected. CCOCs can be painful and the principle clinical sign is swelling, CCOCs can metastasize, and the prognosis is fair.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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فهرسة مساهمة: Keywords: Clear cell odontogenic carcinoma; Immunohistochemistry; Jaws; Malignant odontogenic tumor
تواريخ الأحداث: Date Created: 20211007 Date Completed: 20220830 Latest Revision: 20221014
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9424403
DOI: 10.1007/s12105-021-01383-9
PMID: 34618301
قاعدة البيانات: MEDLINE
الوصف
تدمد:1936-0568
DOI:10.1007/s12105-021-01383-9