دورية أكاديمية
Comparing the evidential strength for psychotropic drugs: a Bayesian meta-analysis.
العنوان: | Comparing the evidential strength for psychotropic drugs: a Bayesian meta-analysis. |
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المؤلفون: | Pittelkow MM; Department Psychometrics and Statistics, University of Groningen, Groningen, the Netherlands., de Vries YA; Department of Developmental Psychology, University of Groningen, Groningen, the Netherlands.; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands., Monden R; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands.; Department of Biomedical Statistics, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Bastiaansen JA; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands.; Department of Education and Research, Friesland Mental Health Care Services, Leeuwarden, the Netherlands., van Ravenzwaaij D; Department Psychometrics and Statistics, University of Groningen, Groningen, the Netherlands. |
المصدر: | Psychological medicine [Psychol Med] 2021 Dec; Vol. 51 (16), pp. 2752-2761. Date of Electronic Publication: 2021 Oct 08. |
نوع المنشور: | Meta-Analysis; Journal Article; Review; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 1254142 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8978 (Electronic) Linking ISSN: 00332917 NLM ISO Abbreviation: Psychol Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: London : Cambridge University Press Original Publication: London, British Medical Assn. |
مواضيع طبية MeSH: | Antipsychotic Agents*/therapeutic use , Attention Deficit Disorder with Hyperactivity*/drug therapy, Humans ; Bayes Theorem ; Psychotropic Drugs/therapeutic use ; Antidepressive Agents/therapeutic use |
مستخلص: | Approval and prescription of psychotropic drugs should be informed by the strength of evidence for efficacy. Using a Bayesian framework, we examined (1) whether psychotropic drugs are supported by substantial evidence (at the time of approval by the Food and Drug Administration), and (2) whether there are systematic differences across drug groups. Data from short-term, placebo-controlled phase II/III clinical trials for 15 antipsychotics, 16 antidepressants for depression, nine antidepressants for anxiety, and 20 drugs for attention deficit hyperactivity disorder (ADHD) were extracted from FDA reviews. Bayesian model-averaged meta-analysis was performed and strength of evidence was quantified (i.e. BF |
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فهرسة مساهمة: | Keywords: Bayesian meta-analysis; drug endorsement; evidential strength; psychotropic drugs |
المشرفين على المادة: | 0 (Antipsychotic Agents) 0 (Psychotropic Drugs) 0 (Antidepressive Agents) |
تواريخ الأحداث: | Date Created: 20211008 Date Completed: 20221124 Latest Revision: 20231108 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC8640368 |
DOI: | 10.1017/S0033291721003950 |
PMID: | 34620261 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1469-8978 |
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DOI: | 10.1017/S0033291721003950 |