دورية أكاديمية
Rhipicephalus microplus: An overview of vaccine antigens against the cattle tick.
| العنوان: | Rhipicephalus microplus: An overview of vaccine antigens against the cattle tick. |
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| المؤلفون: | Pereira DFS; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Ribeiro HS; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Gonçalves AAM; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., da Silva AV; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Lair DF; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., de Oliveira DS; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Boas DFV; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Conrado IDSS; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Leite JC; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Barata LM; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Reis PCC; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Mariano RMDS; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Santos TAP; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Coutinho DCO; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Gontijo NF; Laboratory of Physiology of Hematophagous Insects, Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Araujo RN; Laboratory of Physiology of Hematophagous Insects, Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Galdino AS; Microbial Biotechnology Laboratory, Biochemistry, Federal University of São João Del-Rei, Divinópolis, Minas Gerais, Brazil., Paes PRO; Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Melo MM; Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Nagem RAP; Structural Biology and Biotechnology Laboratory, Department of biochemistry and immunology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Dutra WO; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil., Silveira-Lemos DD; Rosário Vellano University, UNIFENAS, Belo Horizonte, Minas Gerais, Brazil., Rodrigues DS; Santa Rita Experimental Field, EPAMIG Midwest, Prudente de Morais, Minas Gerais, Brazil., Giunchetti RC; Laboratory of Cell-Cell Interactions, Institute of Biological Sciences, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil. Electronic address: giunchetti@icb.ufmg.br. |
| المصدر: | Ticks and tick-borne diseases [Ticks Tick Borne Dis] 2022 Jan; Vol. 13 (1), pp. 101828. Date of Electronic Publication: 2021 Sep 23. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101522599 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-9603 (Electronic) Linking ISSN: 1877959X NLM ISO Abbreviation: Ticks Tick Borne Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier, 2010- |
| مواضيع طبية MeSH: | Cattle Diseases*/prevention & control , Rhipicephalus* , Tick Infestations*/prevention & control , Tick Infestations*/veterinary , Vaccines*, Animals ; Antigens ; Cattle ; Vaccination |
| مستخلص: | Rhipicephalus microplus, popularly known as the cattle tick, is the most important tick of livestock as it is responsible for significant economic losses. The use of chemical acaricides is still the most widely used control method despite its known disadvantages. Vaccination would be a safe alternative for the control of R. microplus and holds advantages over the use of chemical acaricides as it is environmental-friendly and leaves no residues in meat or milk. Two vaccines based on the Bm86 protein were commercialized, TickGARD® and Gavac®, with varying reported efficacies in different countries. The use of other vaccines, such as Tick Vac®, Go-Tick®, and Bovimune Ixovac® have been restricted to some countries. Several other proteins have been analyzed as possible antigens for more effective vaccines against R. microplus, including peptidases, serine proteinase inhibitors, glutathione S-transferases, metalloproteases, and ribosomal proteins, with efficacies ranging from 14% to 96%. Nonetheless, more research is needed to develop safe and efficient tick vaccines, such as the evaluation of the efficacy of antigens against other tick species to verify cross-reactivity and inclusion of additional antigens to promote the blocking of the infection and spreading of tick-borne diseases. This review summarizes the discoveries of candidate antigens for R. microplus tick vaccines as well as the methods used to test their efficacy. (Copyright © 2021. Published by Elsevier GmbH.) |
| فهرسة مساهمة: | Keywords: Efficacy; Peptide; Protein; R. microplus; Vaccination |
| المشرفين على المادة: | 0 (Antigens) 0 (Vaccines) |
| تواريخ الأحداث: | Date Created: 20211010 Date Completed: 20220321 Latest Revision: 20220321 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.ttbdis.2021.101828 |
| PMID: | 34628330 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1877-9603 |
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| DOI: | 10.1016/j.ttbdis.2021.101828 |