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Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams.

التفاصيل البيبلوغرافية
العنوان: Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams.
المؤلفون: Christensen SB; The Museum of Natural Medicine & The Pharmacognostic Collection, University of Copenhagen, Jagtvej 162, DK-2100 Copenhagen, Denmark.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 07; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 07.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c1995-
مواضيع طبية MeSH: Drug Development* , Drug Discovery*, Anti-Bacterial Agents/*chemistry , Anti-Bacterial Agents/*pharmacology , Bacterial Infections/*drug therapy, Arsphenamine/pharmacology ; Humans ; Quality of Life ; Sulfonamides/pharmacology ; beta-Lactams/pharmacology
مستخلص: The appearance of antibiotic drugs revolutionized the possibilities for treatment of diseases with high mortality such as pneumonia, sepsis, plaque, diphtheria, tetanus, typhoid fever, and tuberculosis. Today fewer than 1% of mortalities in high income countries are caused by diseases caused by bacteria. However, it should be recalled that the antibiotics were introduced in parallel with sanitation including sewerage, piped drinking water, high standard of living and improved understanding of the connection between food and health. Development of salvarsan, sulfonamides, and β-lactams into efficient drugs is described. The effects on life expectancy and life quality of these new drugs are indicated.
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فهرسة مساهمة: Keywords: bacterial infectious diseases; carbapenems; cephalosporins; monobactams; penicillins; salvarsan; sulfonamides; thiopenems; β-lactamases
المشرفين على المادة: 0 (Anti-Bacterial Agents)
0 (Sulfonamides)
0 (beta-Lactams)
139-93-5 (Arsphenamine)
تواريخ الأحداث: Date Created: 20211013 Date Completed: 20211116 Latest Revision: 20240817
رمز التحديث: 20240817
مُعرف محوري في PubMed: PMC8512414
DOI: 10.3390/molecules26196057
PMID: 34641601
قاعدة البيانات: MEDLINE
الوصف
تدمد:1420-3049
DOI:10.3390/molecules26196057