دورية أكاديمية
Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams.
العنوان: | Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams. |
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المؤلفون: | Christensen SB; The Museum of Natural Medicine & The Pharmacognostic Collection, University of Copenhagen, Jagtvej 162, DK-2100 Copenhagen, Denmark. |
المصدر: | Molecules (Basel, Switzerland) [Molecules] 2021 Oct 07; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 07. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, c1995- |
مواضيع طبية MeSH: | Drug Development* , Drug Discovery*, Anti-Bacterial Agents/*chemistry , Anti-Bacterial Agents/*pharmacology , Bacterial Infections/*drug therapy, Arsphenamine/pharmacology ; Humans ; Quality of Life ; Sulfonamides/pharmacology ; beta-Lactams/pharmacology |
مستخلص: | The appearance of antibiotic drugs revolutionized the possibilities for treatment of diseases with high mortality such as pneumonia, sepsis, plaque, diphtheria, tetanus, typhoid fever, and tuberculosis. Today fewer than 1% of mortalities in high income countries are caused by diseases caused by bacteria. However, it should be recalled that the antibiotics were introduced in parallel with sanitation including sewerage, piped drinking water, high standard of living and improved understanding of the connection between food and health. Development of salvarsan, sulfonamides, and β-lactams into efficient drugs is described. The effects on life expectancy and life quality of these new drugs are indicated. |
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فهرسة مساهمة: | Keywords: bacterial infectious diseases; carbapenems; cephalosporins; monobactams; penicillins; salvarsan; sulfonamides; thiopenems; β-lactamases |
المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Sulfonamides) 0 (beta-Lactams) 139-93-5 (Arsphenamine) |
تواريخ الأحداث: | Date Created: 20211013 Date Completed: 20211116 Latest Revision: 20240817 |
رمز التحديث: | 20240817 |
مُعرف محوري في PubMed: | PMC8512414 |
DOI: | 10.3390/molecules26196057 |
PMID: | 34641601 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1420-3049 |
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DOI: | 10.3390/molecules26196057 |