دورية أكاديمية
Magnetic resonance imaging before breast cancer surgery: results of an observational multicenter international prospective analysis (MIPA).
| العنوان: | Magnetic resonance imaging before breast cancer surgery: results of an observational multicenter international prospective analysis (MIPA). |
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| المؤلفون: | Sardanelli F; Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy. francesco.sardanelli@unimi.it.; Unit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy. francesco.sardanelli@unimi.it., Trimboli RM; Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy., Houssami N; Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Gilbert FJ; Department of Radiology, School of Clinical Medicine, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Helbich TH; Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Research Group: Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria., Álvarez Benito M; Department of Radiology, Hospital Universitario Reina Sofía, Córdoba, Spain., Balleyguier C; Department of Radiology, Institut Gustave Roussy, Villejuif, France., Bazzocchi M; Institute of Radiology, Department of Medicine, Università degli Studi di Udine, Udine, Italy., Bult P; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Calabrese M; Unit of Breast Radiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Camps Herrero J; Department of Radiology, Hospital Universitario de La Ribera, Alzira, Spain., Cartia F; Unit of Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Cassano E; Breast Imaging Division, IEO, European Institute of Oncology IRCCS, Milan, Italy., Clauser P; Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Research Group: Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria., Cozzi A; Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy., de Andrade DA; Department of Breast Surgery, Hospital Sírio Libanês, São Paulo, Brazil., de Lima Docema MF; Department of Radiology, Hospital Sírio Libanês, São Paulo, Brazil., Depretto C; Unit of Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Dominelli V; Breast Imaging Division, IEO, European Institute of Oncology IRCCS, Milan, Italy., Forrai G; Department of Radiology, MHEK Teaching Hospital, Semmelweis University, Budapest, Hungary., Girometti R; Institute of Radiology, Department of Medicine, Università degli Studi di Udine, Udine, Italy., Harms SE; Breast Center of Northwest Arkansas, Fayetteville, AR, USA., Hilborne S; Department of Radiology, School of Clinical Medicine, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Ienzi R; Department of Radiology, Di.Bi.MED, Università degli Studi di Palermo, Policlinico Universitario Paolo Giaccone, Palermo, Italy., Lobbes MBI; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands., Losio C; Department of Breast Radiology, IRCCS Ospedale San Raffaele, Milan, Italy., Mann RM; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Montemezzi S; Department of Radiology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Obdeijn IM; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Ozcan UA; Unit of Radiology, Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey., Pediconi F; Department of Radiological, Oncological and Pathological Sciences, Università degli Studi di Roma 'La Sapienza', Rome, Italy., Pinker K; Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Research Group: Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.; Department of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Preibsch H; Department of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany., Raya Povedano JL; Department of Radiology, Hospital Universitario Reina Sofía, Córdoba, Spain., Sacchetto D; Kiwifarm S.R.L, La Morra, Italy.; Disaster Medicine Service 118, ASL CN1, Saluzzo, Italy.; CRIMEDIM, Research Center in Emergency and Disaster Medicine, Università degli Studi del Piemonte Orientale 'Amedeo Avogadro', Novara, Italy., Scaperrotta GP; Unit of Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Schiaffino S; Unit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy., Schlooz M; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., Szabó BK; Department of Radiology, Barking Havering and Redbridge University Hospitals NHS Trust, London, UK., Taylor DB; Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.; Department of Radiology, Royal Perth Hospital, Perth, Australia., Ulus ÖS; Unit of Radiology, Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey., Van Goethem M; Gynecological Oncology Unit, Department of Obstetrics and Gynecology, Department of Radiology, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium., Veltman J; Maatschap Radiologie Oost-Nederland, Oldenzaal, The Netherlands., Weigel S; Institute of Clinical Radiology and Reference Center for Mammography, University of Münster, Münster, Germany., Wenkel E; Department of Radiology, University Hospital of Erlangen, Erlangen, Germany., Zuiani C; Institute of Radiology, Department of Medicine, Università degli Studi di Udine, Udine, Italy., Di Leo G; Unit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy. |
| المصدر: | European radiology [Eur Radiol] 2022 Mar; Vol. 32 (3), pp. 1611-1623. Date of Electronic Publication: 2021 Oct 13. |
| نوع المنشور: | Journal Article; Multicenter Study; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer International Country of Publication: Germany NLM ID: 9114774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1084 (Electronic) Linking ISSN: 09387994 NLM ISO Abbreviation: Eur Radiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Berlin : Springer International, c1991- |
| مواضيع طبية MeSH: | Breast Neoplasms*/diagnostic imaging , Breast Neoplasms*/surgery, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Breast ; Female ; Humans ; Magnetic Resonance Imaging ; Mastectomy ; Mastectomy, Segmental ; Middle Aged ; Preoperative Care ; Young Adult |
| مستخلص: | Objectives: Preoperative breast magnetic resonance imaging (MRI) can inform surgical planning but might cause overtreatment by increasing the mastectomy rate. The Multicenter International Prospective Analysis (MIPA) study investigated this controversial issue. Methods: This observational study enrolled women aged 18-80 years with biopsy-proven breast cancer, who underwent MRI in addition to conventional imaging (mammography and/or breast ultrasonography) or conventional imaging alone before surgery as routine practice at 27 centers. Exclusion criteria included planned neoadjuvant therapy, pregnancy, personal history of any cancer, and distant metastases. Results: Of 5896 analyzed patients, 2763 (46.9%) had conventional imaging only (noMRI group), and 3133 (53.1%) underwent MRI that was performed for diagnosis, screening, or unknown purposes in 692/3133 women (22.1%), with preoperative intent in 2441/3133 women (77.9%, MRI group). Patients in the MRI group were younger, had denser breasts, more cancers ≥ 20 mm, and a higher rate of invasive lobular histology than patients who underwent conventional imaging alone (p < 0.001 for all comparisons). Mastectomy was planned based on conventional imaging in 22.4% (MRI group) versus 14.4% (noMRI group) (p < 0.001). The additional planned mastectomy rate in the MRI group was 11.3%. The overall performed first- plus second-line mastectomy rate was 36.3% (MRI group) versus 18.0% (noMRI group) (p < 0.001). In women receiving conserving surgery, MRI group had a significantly lower reoperation rate (8.5% versus 11.7%, p < 0.001). Conclusions: Clinicians requested breast MRI for women with a higher a priori probability of receiving mastectomy. MRI was associated with 11.3% more mastectomies, and with 3.2% fewer reoperations in the breast conservation subgroup. Key Points: • In 19% of patients of the MIPA study, breast MRI was performed for screening or diagnostic purposes. • The current patient selection to preoperative breast MRI implies an 11% increase in mastectomies, counterbalanced by a 3% reduction of the reoperation rate. • Data from the MIPA study can support discussion in tumor boards when preoperative MRI is under consideration and should be shared with patients to achieve informed decision-making. (© 2021. The Author(s).) |
| References: | Lehman CD, Gatsonis C, Kuhl CK et al (2007) MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer. N Engl J Med 356:1295–1303. https://doi.org/10.1056/NEJMoa065447. (PMID: 10.1056/NEJMoa06544717392300) Ray KM, Hayward JH, Joe BN (2018) Role of MR imaging for the locoregional staging of breast cancer. Magn Reson Imaging Clin N Am 26:191–205. https://doi.org/10.1016/j.mric.2017.12.008. (PMID: 10.1016/j.mric.2017.12.00829622125) Houssami N, Turner R, Macaskill P et al (2014) An individual person data meta-analysis of preoperative magnetic resonance imaging and breast cancer recurrence. J Clin Oncol 32:392–401. https://doi.org/10.1200/JCO.2013.52.7515. (PMID: 10.1200/JCO.2013.52.751524395846) Houssami N, Turner RM, Morrow M (2017) Meta-analysis of pre-operative magnetic resonance imaging (MRI) and surgical treatment for breast cancer. Breast Cancer Res Treat 165:273–283. https://doi.org/10.1007/s10549-017-4324-3. (PMID: 10.1007/s10549-017-4324-3285893665580248) Monticciolo DL (2017) Practical considerations for the use of breast MRI for breast cancer evaluation in the preoperative setting. Acad Radiol 24:1447–1450. https://doi.org/10.1016/j.acra.2017.05.012. (PMID: 10.1016/j.acra.2017.05.01228647387) Sardanelli F, Newstead GM, Putz B et al (2016) Gadobutrol-enhanced magnetic resonance imaging of the breast in the preoperative setting. Invest Radiol 51:454–461. https://doi.org/10.1097/RLI.0000000000000254. (PMID: 10.1097/RLI.000000000000025426840494) Plana MN, Carreira C, Muriel A et al (2012) Magnetic resonance imaging in the preoperative assessment of patients with primary breast cancer: systematic review of diagnostic accuracy and meta-analysis. Eur Radiol 22:26–38. https://doi.org/10.1007/s00330-011-2238-8. (PMID: 10.1007/s00330-011-2238-821847541) Jatoi I, Benson JR (2013) The case against routine preoperative breast MRI. Futur Oncol 9:347–353. https://doi.org/10.2217/fon.12.186. (PMID: 10.2217/fon.12.186) Arnaout A, Catley C, Booth CM et al (2015) Use of preoperative magnetic resonance imaging for breast cancer. JAMA Oncol 1:1238–1250. https://doi.org/10.1001/jamaoncol.2015.3018. (PMID: 10.1001/jamaoncol.2015.301826402040) Zeng Z, Amin A, Roy A et al (2020) Preoperative magnetic resonance imaging use and oncologic outcomes in premenopausal breast cancer patients. NPJ Breast Cancer 6:49. https://doi.org/10.1038/s41523-020-00192-7. (PMID: 10.1038/s41523-020-00192-7330835287532157) Sardanelli F, Boetes C, Borisch B et al (2010) Magnetic resonance imaging of the breast: Recommendations from the EUSOMA working group. Eur J Cancer 46:1296–1316. https://doi.org/10.1016/j.ejca.2010.02.015. (PMID: 10.1016/j.ejca.2010.02.01520304629) Mann RM, Balleyguier C, Baltzer PA et al (2015) Breast MRI: EUSOBI recommendations for women’s information. Eur Radiol 25:3669–3678. https://doi.org/10.1007/s00330-015-3807-z. (PMID: 10.1007/s00330-015-3807-z260021304636525) The American Society of Breast Surgeons (2016) Don’t routinely order breast MRI in new breast cancer patients. The American Society of Breast Surgeons, Columbia, MD, USA. Available via https://www.choosingwisely.org/societies/american-society-of-breast-surgeons/ . Accessed 01 Jun 2021. Sardanelli F, Trimboli RM, Houssami N et al (2020) Solving the preoperative breast MRI conundrum: design and protocol of the MIPA study. Eur Radiol 30(10):5427–5436. https://doi.org/10.1007/s00330-020-06824-7. (PMID: 10.1007/s00330-020-06824-732377813) Newell MS, Giess CS, Argus AD et al (2018) ACR practice parameter for the performance of contrast-enhanced magnetic resonance imaging (MRI) of the breast. American College of Radiology, Reston, VA, USA. Available via https://www.acr.org/-/media/ACR/Files/Practice-Parameters/MR-Contrast-Breast.pdf . Accessed 01 Jun 2021. Parker A, Schroen AT, Brenin DR (2013) MRI utilization in newly diagnosed breast cancer: a survey of practicing surgeons. Ann Surg Oncol 20:2600–2606. https://doi.org/10.1245/s10434-013-2934-5. (PMID: 10.1245/s10434-013-2934-523515911) Lee J, Tanaka E, Eby PR et al (2017) Preoperative breast MRI: surgeons’ patient selection patterns and potential bias in outcomes analyses. AJR Am J Roentgenol 208:923–932. https://doi.org/10.2214/AJR.16.17038. (PMID: 10.2214/AJR.16.1703828026205) McLaughlin SA (2013) Surgical management of the breast. Surg Clin North Am 93:411–428. https://doi.org/10.1016/j.suc.2012.12.006. (PMID: 10.1016/j.suc.2012.12.00623464693) Margenthaler JA, Ollila DW (2016) Breast conservation therapy versus mastectomy: shared decision-making strategies and overcoming decisional conflicts in your patients. Ann Surg Oncol 23:3133–3137. https://doi.org/10.1245/s10434-016-5369-y. (PMID: 10.1245/s10434-016-5369-y27464606) Tot T, Gere M (2008) Radiological–pathological correlation in diagnosing breast carcinoma: the role of pathology in the multimodality era. Pathol Oncol Res 14:173–178. https://doi.org/10.1007/s12253-008-9061-9. (PMID: 10.1007/s12253-008-9061-918521722) Gonzalez V, Sandelin K, Karlsson A et al (2014) Preoperative MRI of the breast (POMB) influences primary treatment in breast cancer: a prospective, randomized, multicenter study. World J Surg 38:1685–1693. https://doi.org/10.1007/s00268-014-2605-0. (PMID: 10.1007/s00268-014-2605-024817517) Balleyguier C, Dunant A, Ceugnart L et al (2019) Preoperative breast magnetic resonance imaging in women with local ductal carcinoma in situ to optimize surgical outcomes: results from the randomized phase III trial IRCIS. J Clin Oncol 37:885–892. https://doi.org/10.1200/JCO.18.00595. (PMID: 10.1200/JCO.18.0059530811290) Walsh SM, Brennan SB, Zabor EC et al (2019) Does breast density increase the risk of re-excision for women with breast cancer having breast-conservation therapy? Ann Surg Oncol 26:4246–4253. https://doi.org/10.1245/s10434-019-07647-7. (PMID: 10.1245/s10434-019-07647-7313967836868322) McCahill LE, Single RM, Aiello Bowles EJ et al (2012) Variability in reexcision following breast conservation surgery. JAMA 307:467–475. https://doi.org/10.1001/jama.2012.43. (PMID: 10.1001/jama.2012.4322298678) Landercasper J, Borgert AJ, Fayanju OM et al (2019) Factors associated with reoperation in breast-conserving surgery for cancer: a prospective study of american society of breast surgeon members. Ann Surg Oncol 26:3321–3336. https://doi.org/10.1245/s10434-019-07547-w. (PMID: 10.1245/s10434-019-07547-w313423606733824) Turnbull L, Brown S, Harvey I et al (2010) Comparative effectiveness of MRI in breast cancer (COMICE) trial: a randomised controlled trial. Lancet 375:563–571. https://doi.org/10.1016/S0140-6736(09)62070-5. (PMID: 10.1016/S0140-6736(09)62070-520159292) Peters NHGM, van Esser S, van den Bosch MAAJ et al (2011) Preoperative MRI and surgical management in patients with nonpalpable breast cancer: The MONET – Randomised controlled trial. Eur J Cancer 47:879–886. https://doi.org/10.1016/j.ejca.2010.11.035. (PMID: 10.1016/j.ejca.2010.11.03521195605) Heil J, Breitkreuz K, Golatta M et al (2012) Do reexcisions impair aesthetic outcome in breast conservation surgery? exploratory analysis of a prospective cohort study. Ann Surg Oncol 19:541–547. https://doi.org/10.1245/s10434-011-1947-1. (PMID: 10.1245/s10434-011-1947-121761099) Olsen MA, Nickel KB, Margenthaler JA et al (2015) Increased risk of surgical site infection among breast-conserving surgery re-excisions. Ann Surg Oncol 22:2003–2009. https://doi.org/10.1245/s10434-014-4200-x. (PMID: 10.1245/s10434-014-4200-x25358666) Nabhan C, Klink A, Prasad V (2019) Real-world evidence—what does it really mean? JAMA Oncol 5:781–783. https://doi.org/10.1001/jamaoncol.2019.0450. (PMID: 10.1001/jamaoncol.2019.045031095259) |
| معلومات مُعتمدة: | P30 CA008748 United States CA NCI NIH HHS |
| فهرسة مساهمة: | Keywords: Breast cancer; Breast-conserving surgery; Magnetic resonance imaging; Mastectomy; Reoperation |
| تواريخ الأحداث: | Date Created: 20211013 Date Completed: 20220214 Latest Revision: 20220514 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8831264 |
| DOI: | 10.1007/s00330-021-08240-x |
| PMID: | 34643778 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1432-1084 |
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| DOI: | 10.1007/s00330-021-08240-x |