دورية أكاديمية
Fluvastatin combined with corbrin capsule can improve depression and anxiety in the treatment of chronic obstructive pulmonary disease.
| العنوان: | Fluvastatin combined with corbrin capsule can improve depression and anxiety in the treatment of chronic obstructive pulmonary disease. |
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| المؤلفون: | Zhu J; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Yan L; Department of Anesthesiology, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Ji JN; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Chen F; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Mei LB; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Cheng N; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Shan ZM; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China., Wang JB; The Third Ward of Cadre Health Center, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001, China. |
| المصدر: | American journal of translational research [Am J Transl Res] 2021 Sep 15; Vol. 13 (9), pp. 10501-10508. Date of Electronic Publication: 2021 Sep 15 (Print Publication: 2021). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101493030 Publication Model: eCollection Cited Medium: Print ISSN: 1943-8141 (Print) Linking ISSN: 19438141 NLM ISO Abbreviation: Am J Transl Res Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Madison, WI : e-Century Pub. Corp. |
| مستخلص: | Objective: To investigate the effect of fluvastatin (Flu) combined with corbrin capsule (CC) on the pulmonary function (PF) in patients with chronic obstructive pulmonary disease (COPD). Methods: Totally, 156 patients with COPD treated in our hospital were assigned: 86 patients in the research group (RG), who were treated with Flu plus CC, and 70 patients in the control group (CG), who were treated with CC plus conventional drugs. The changes in inflammatory factors, including interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α) and procalcitonin (PCT), of the two groups before and after treatment were compared. The complications, psychological status, quality of life (QOL) and recurrence rate of the two groups were analyzed. Results: The total effective rate in the RG was dramatically higher than that in the CG (P<0.05). Compared with the factors in the CG, the PF in the RG notably increased after treatment (P<0.05); the blood gas levels were noticeably better (P<0.05); and the level of inflammatory factors decreased (P<0.05). The incidence of complications in the RG was noticeably lower than that in the CG (P<0.05). The psychological status and QOL in the RG were remarkably better than those in the CG (P<0.05), and the recurrence rate within one year of diagnosis was lower than that in the CG (P<0.05). Conclusion: Flu combined with CC is effective and safe in the treatment of COPD and can effectively improve the PF and the QOL of patients. Competing Interests: None. (AJTR Copyright © 2021.) |
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| فهرسة مساهمة: | Keywords: Flu combined with CC; chronic obstructive pulmonary disease; pulmonary function; quality of life |
| تواريخ الأحداث: | Date Created: 20211015 Latest Revision: 20211016 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8507000 |
| PMID: | 34650720 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1943-8141 |
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