دورية أكاديمية
Role and utility of COVID-19 laboratory testing in low-income and middle-income countries: protocol for rapid evidence synthesis.
| العنوان: | Role and utility of COVID-19 laboratory testing in low-income and middle-income countries: protocol for rapid evidence synthesis. |
|---|---|
| المؤلفون: | Ouma OK; Department of Medicine, Clinical Epidemiology Unit, Makerere University College of Health Sciences, Kampala, Uganda.; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda., Ephraim K; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of General Medicine, Kairos Hospital, Kampala, Uganda., Loyce N; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of Pharmacology, College of Medicine and Health Sciences, King Ceasor University, Kampala, Uganda., Namisango E; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, King's College Hospital, London, UK., Nalugoda F; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; School of Public Health, Rakai Health Sciences Program, Makerere University College of Health Sciences, Kampala, Uganda., Ndagire R; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of General Medicine, Kairos Hospital, Kampala, Uganda., Wangi RN; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of General Medicine, Kairos Hospital, Kampala, Uganda., Kawala BA; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of Public Health, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Katairo T; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Laboratory, Infectious Diseases Research Collaboration, Kampala, Uganda., Okullo AE; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of Medicine, Makerere University, Kampala, Uganda., Apunyo R; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda., Semakula D; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of Medicine, Regional East African Community Health (REACH) Policy Initiative, Makerere University College of Health Sciences, Kampala, Uganda., Luwambo A; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Directorate for ICT Support, Makerere University College of Health Sciences, Kampala, Uganda., Kinengyere AA; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Albert Cook Library, Makerere University College of Health Sciences, Kampala, Uganda., Sewankambo N; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda., Balinda SN; Pathogen Genomics, Phenotype and Immunity, Uganda Virus Research Institute, Entebbe, Uganda., Ocan M; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda ocanmoses@gmail.com.; Department of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda., Obuku EA; Africa Centre for Systematic Reviews and Knowledge Translation, Makerere University College of Health Sciences, Kampala, Uganda.; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. |
| المصدر: | BMJ open [BMJ Open] 2021 Oct 18; Vol. 11 (10), pp. e050296. Date of Electronic Publication: 2021 Oct 18. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BMJ Publishing Group Ltd, 2011- |
| مواضيع طبية MeSH: | COVID-19* , Developing Countries*, Humans ; Income ; Review Literature as Topic ; SARS-CoV-2 |
| مستخلص: | Introduction: Accurate and affordable laboratory testing is key to timely diagnosis and appropriate management of patients with COVID-19. New laboratory test protocols are released into the market under emergency use authorisation with limited evidence on diagnostic test accuracy. As such, robust evidence on the diagnostic accuracy and the costs of available tests is urgently needed to inform policy and practice especially in resource-limited settings. We aim to determine the diagnostic test accuracy, cost-effectiveness and utility of laboratory test strategies for COVID-19 in low-income and middle-income countries. Methods and Analysis: This will be a multistaged, protocol-driven systematic review conducted in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for diagnostic test accuracy studies. We will search for relevant literature in at least six public health databases, including PubMed, Google Scholar, MEDLINE, Scopus, Web of Science and the WHO Global Index Medicus. In addition, we will search Cochrane Library, COVID-END and grey literature databases to identify additional relevant articles before double-screening and abstraction of data. We will conduct a structured narrative and quantitative synthesis of the results guided by the Fryback and Thornbury framework for assessing a diagnostic test. The primary outcome is COVID-19 diagnostic test accuracy. Using the GRADE approach specific to diagnostic accuracy tests, we will appraise the overall quality of evidence and report the results following the original PRISMA statement. The protocol is registered with the International Prospective Register of Systematic Reviews (PROSPERO; https://www.crd.york.ac.uk/prospero/). Ethics and Dissemination: Ethical review was done by the School of Biomedical Sciences Research Ethics Committee and the Uganda National Council for Science and Technology. The published article will be accessible to policy and decision makers. The findings of this review will guide clinical practice and policy decisions and highlight areas for future research. PROSPERO registration number CRD42020209528. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
| References: | J Clin Epidemiol. 2019 Jul;111:105-114. (PMID: 29432858) Int J Epidemiol. 2008 Oct;37(5):1158-60. (PMID: 18832388) Med Decis Making. 1991 Apr-Jun;11(2):88-94. (PMID: 1907710) PLoS Biol. 2020 Oct 2;18(10):e3000896. (PMID: 33006983) Biometrics. 2000 Jun;56(2):455-63. (PMID: 10877304) BMJ. 2017 Sep 21;358:j4008. (PMID: 28935701) BMJ. 1997 Sep 13;315(7109):629-34. (PMID: 9310563) Cochrane Database Syst Rev. 2020 Aug 26;8:CD013705. (PMID: 32845525) J Med Virol. 2021 Jan;93(1):441-447. (PMID: 32592502) BMJ. 2020 Jul 1;370:m2516. (PMID: 32611558) BMJ. 2020 Aug 14;370:m2632. (PMID: 32816740) Expert Rev Mol Diagn. 2020 May;20(5):453-454. (PMID: 32297805) New Sci. 2020 May 16;246(3282):13. (PMID: 32501339) Ann Intern Med. 2011 Oct 18;155(8):529-36. (PMID: 22007046) |
| فهرسة مساهمة: | Keywords: COVID-19; infectious diseases; infectious diseases & infestations; microbiology; protocols & guidelines |
| تواريخ الأحداث: | Date Created: 20211019 Date Completed: 20211029 Latest Revision: 20220531 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8523956 |
| DOI: | 10.1136/bmjopen-2021-050296 |
| PMID: | 34663660 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2044-6055 |
|---|---|
| DOI: | 10.1136/bmjopen-2021-050296 |