دورية أكاديمية

Seroconversion of rheumatoid arthritis patients after yellow fever vaccination.

التفاصيل البيبلوغرافية
العنوان: Seroconversion of rheumatoid arthritis patients after yellow fever vaccination.
المؤلفون: Dos Reis BS; Pontifícia Universidade Católica do Paraná - PUCPR, Curitiba, Paraná, Brazil., Staub FC; Pontifícia Universidade Católica do Paraná - PUCPR, Curitiba, Paraná, Brazil., Koishi A; Laboratório de Virologia Molecular, Instituto Carlos Chagas/Fiocruz PR, Curitiba, , Paraná, Brazil., Zanluca C; Laboratório de Virologia Molecular, Instituto Carlos Chagas/Fiocruz PR, Curitiba, , Paraná, Brazil., Dos Santos CND; Laboratório de Virologia Molecular, Instituto Carlos Chagas/Fiocruz PR, Curitiba, , Paraná, Brazil., Skare TL; Rheumatology Unit, Hospital Evangélico Mackenzie, Professor Ulisses Vieira, 145 ap 54 - Vila Izabel, Curitiba, Paraná, CEP 80320-090, Brazil., Kahlow BS; Pontifícia Universidade Católica do Paraná - PUCPR, Curitiba, Paraná, Brazil. bazinha_st@yahoo.com.br.; Rheumatology Unit, Hospital Evangélico Mackenzie, Professor Ulisses Vieira, 145 ap 54 - Vila Izabel, Curitiba, Paraná, CEP 80320-090, Brazil. bazinha_st@yahoo.com.br.
المصدر: Clinical rheumatology [Clin Rheumatol] 2022 Mar; Vol. 41 (3), pp. 705-708. Date of Electronic Publication: 2021 Oct 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949 (Electronic) Linking ISSN: 07703198 NLM ISO Abbreviation: Clin Rheumatol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2008->: Heidelberg : Springer
Original Publication: Brussels : Acta Medica Belgica, [1982-
مواضيع طبية MeSH: Arthritis, Rheumatoid*/drug therapy , Yellow Fever*/prevention & control, Antibodies, Neutralizing ; Antibodies, Viral ; Female ; Humans ; Male ; Middle Aged ; Seroconversion ; Vaccination
مستخلص: Vaccination is a current strategy used to prevent infections in patients with immune-mediated rheumatic diseases. However, the use of live-attenuated vaccines prepared from living microorganisms in these patients should be avoided due to the risk of acquiring infections. The present study aimed to investigate the effect of the yellow fever (YF) vaccine (a live-attenuated vaccine) in 12 patients with rheumatoid arthritis (RA). The sample comprised 12 patients (9 females and 3 males; mean age 52.2 ± 6.5 years) with RA, who inadvertently received fractionated 17D yellow fever vaccination during an outbreak of this disease. In this cohort, 10 were administered leflunomide; 7 were administered methotrexate; 6 were administered prednisone (median dose of 5.0 mg/day); 6 took biologic drugs; and 1 took tofacitinib. All but one patient (used rituximab, prednisone, and methotrexate) seroconverted. None of them developed clinical signs of infection after the procedure. The fractionated dose of the YF vaccine is effective and safe in the observed sample. Key Points • Patients with autoimmune inflammatory rheumatic diseases (AIIRD) are at a high risk of acquiring infections • The fractionated dose of the YF vaccine is effective and safe in the observed sample • Vaccination against YF should be avoided in patients with AIIRD under immunosuppression owing to the risks of inducing YF infection.
(© 2021. International League of Associations for Rheumatology (ILAR).)
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فهرسة مساهمة: Keywords: Live-attenuated vaccine; Neutralizing antibodies; Rheumatoid arthritis; Yellow fever
المشرفين على المادة: 0 (Antibodies, Neutralizing)
0 (Antibodies, Viral)
تواريخ الأحداث: Date Created: 20211021 Date Completed: 20220228 Latest Revision: 20220614
رمز التحديث: 20231215
DOI: 10.1007/s10067-021-05962-7
PMID: 34674083
قاعدة البيانات: MEDLINE
الوصف
تدمد:1434-9949
DOI:10.1007/s10067-021-05962-7