دورية أكاديمية
Isolation and molecular characterization of multidrug-resistant Salmonella enterica serovars.
| العنوان: | Isolation and molecular characterization of multidrug-resistant Salmonella enterica serovars. |
|---|---|
| المؤلفون: | Al-Ansari MM; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: myalansari@ksu.edu.sa., Aljubali MM; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Somily AM; College of Medicine, King Saud University Medical City, Microbiology (32), PO Box 2925, Riyadh 11461, Saudi Arabia., Albarrag AM; Department of Pathology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia., Masood A; Department of Proteomics, College of Medicine, King Saud University, P.O. Box-2925, Riyadh 11451, Saudi Arabia. |
| المصدر: | Journal of infection and public health [J Infect Public Health] 2021 Dec; Vol. 14 (12), pp. 1767-1776. Date of Electronic Publication: 2021 Oct 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 101487384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-035X (Electronic) Linking ISSN: 18760341 NLM ISO Abbreviation: J Infect Public Health Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford : Elsevier, 2008- |
| مواضيع طبية MeSH: | Salmonella Infections, Animal* , Salmonella enterica*/genetics, Animals ; Anti-Bacterial Agents/pharmacology ; Chickens ; Drug Resistance, Multiple, Bacterial/genetics ; Humans ; Salmonella enteritidis/genetics ; Serogroup |
| مستخلص: | Background: Salmonellosis is a foodborne zoonosis leaving gastrointestinal illness and drug-resistant genes to the consumers. To prevent Salmonella contamination associated health issues in the chicken meat sold in Riyadh city in Saudi Arabia. The evaluation of the Salmonella isolates from the meat sample needs to be screened for the composition of Salmonella serotypes and antimicrobial resistance pattern at the molecular level. Methods and Results: Using specific growth media for Salmonella spp., swabs taken from the whole-body surfaces of 200 chilled broiler chickens from different vendors in the city of Riyadh, were screened for Salmonella contamination. Biochemical and molecular characterization of the isolates showed the presence of the serovars, Salmonella enterica, Salmonella Enteritidis, S. Typhimurium, S. Kentucky, and S. Tennessee. The isolated serovars exhibited multidrug resistance [MDR] resistance to antibiotics. Molecular characterization of the different serovars shows the presence of sixteen drug-resistant genes. The drug resistance mechanism at the molecular level varied with serotypes according to the nature of the antibiotics they encountered. A comparative study of the nature of the drug-resistant gene and the common antibiotics used in poultry farming in that province matches much, indicating adaptive variation in S. enterica serotypes to survive in the host's gut biome. The resistance genes from the chicken meat have every chance to get into the human system. The native microbes in consumers may acquire drug-resistant genes from S. entericus serovars. Such conditions may lead to treatment complications in the hosts. Conclusions: The results indicated that Salmonella infections constituted a potential risk to consumers through chicken flocks and noted that the genotypic resistance pattern to antibiotics draws attention in terms of both human and animal health. Also, promote other options for poultry farming, avoiding antibiotics supplementation. (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antibiotic resistance profiling; Chicken; PCR characterization; Salmonella |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20211025 Date Completed: 20211213 Latest Revision: 20211214 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.jiph.2021.10.011 |
| PMID: | 34690097 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1876-035X |
|---|---|
| DOI: | 10.1016/j.jiph.2021.10.011 |