دورية أكاديمية
Association of Self-Rated Health With Functional Limitations in Patients With CKD.
العنوان: | Association of Self-Rated Health With Functional Limitations in Patients With CKD. |
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المؤلفون: | Lee J; Department of Medicine, School of Medicine, Pittsburgh, PA., Abdel-Kader K; Vanderbilt University, Nephrology and Hypertension Division, Nashville, TN., Yabes JG; Center for Research on Health Care, Division of General Internal Medicine, Pittsburgh, PA., Cai M; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA., Chang HH; Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan., Jhamb M; Renal-Electrolyte Division, Pittsburgh, PA. |
المصدر: | Kidney medicine [Kidney Med] 2021 Jun 25; Vol. 3 (5), pp. 745-752.e1. Date of Electronic Publication: 2021 Jun 25 (Print Publication: 2021). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101756300 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-0595 (Electronic) Linking ISSN: 25900595 NLM ISO Abbreviation: Kidney Med Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: [Cambridge, MA] : Elsevier Inc., [2019]- |
مستخلص: | Rationale & Objective: In patients with chronic kidney disease (CKD), self-rated health ("In general, how do you rate your health?") is associated with mortality. The association of self-rated health with functional status is unknown. We evaluated the association of limitations in activities of daily living (ADLs) with self-rated health and clinical correlates in a cohort of patients with CKD stages 1-5. Study Design: Prospective cohort study. Setting & Participants: Patients with CKD at a nephrology outpatient clinic in western Pennsylvania. Outcome: Patients participated in a survey assessing their self-rated health (5-point Likert scale) and physical (ambulation, dressing, shopping) and cognitive (executive and memory) ADLs. Adjusted analysis was performed using logistic regression models. Analytical Approach: Logistic regression was conducted to examine the adjusted association of 3 dependent variables (sum of total, physical, and cognitive ADL limitations) with self-rated health (independent variable of interest). Results: The survey was completed by 1,268 participants (mean age, 60 years; 49% females, and 74% CKD stages 3-5), of which 41% reported poor-to-fair health. Overall, 35.9% had at least 1 physical ADL limitation, 22.1% had at least 1 cognitive ADL limitation, and 12.5% had at least 3 ADL limitations. Ambulation was the most frequently reported limitation and was more common in patients reporting poor-to-fair self-rated health compared with those with good-to-excellent self-rated health (58.1% vs 17.4%, P < 0.001). In our fully adjusted model, poor-to-fair self-rated health was strongly associated with limitations in at least 3 ADLs (total ADL) [OR 8.29 (95% CI, 5.23-13.12)]. There was no significant association of eGFR with ADL limitations. Limitations: Selection bias due to optional survey completion, residual confounding, and use of abbreviated (as opposed to full) ADL questionnaires. Conclusions: Poor-to-fair self-rated health is strongly associated with physical ADL limitations in patients with CKD. Future studies should evaluate whether self-rated health questions may be useful for identifying patients who can benefit from additional evaluation and treatment of functional limitations to improve patient-centered outcomes. (© 2021 The Authors.) |
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معلومات مُعتمدة: | P30 DK079307 United States DK NIDDK NIH HHS |
فهرسة مساهمة: | Keywords: Ambulation; chronic kidney disease; cognitive function; executive function; functional status; instrumental activities of daily living; limitations in activities of daily living; quality of life; self-rated health |
تواريخ الأحداث: | Date Created: 20211025 Latest Revision: 20220427 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC8515078 |
DOI: | 10.1016/j.xkme.2021.04.010 |
PMID: | 34693255 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2590-0595 |
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DOI: | 10.1016/j.xkme.2021.04.010 |