دورية أكاديمية

Comparison of right-to-left shunt characteristics in cryptogenic embolic ischemic stroke and non-cardioembolic ischemic stroke.

التفاصيل البيبلوغرافية
العنوان: Comparison of right-to-left shunt characteristics in cryptogenic embolic ischemic stroke and non-cardioembolic ischemic stroke.
المؤلفون: Scavasine VC; Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Neurologia, Curitiba PR, Brazil., Chamma JF; Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Neurologia, Curitiba PR, Brazil., Bazan R; Universidade Estadual Paulista 'Júlio de Mesquita Filho', Departamento de Neurologia, Botucatu SP, Brazil., Braga GP; Universidade Federal de Mato Grosso do Sul, Departamento de Neurologia, Campo Grande MS, Brazil., Lange MC; Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Neurologia, Curitiba PR, Brazil., Zétola VHF; Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Neurologia, Curitiba PR, Brazil.
المصدر: Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2021 Oct; Vol. 79 (10), pp. 859-863.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Thieme Country of Publication: Germany NLM ID: 0125444 Publication Model: Print Cited Medium: Internet ISSN: 1678-4227 (Electronic) Linking ISSN: 0004282X NLM ISO Abbreviation: Arq Neuropsiquiatr Subsets: MEDLINE
أسماء مطبوعة: Publication: 2022- : [Stuttgart] : Thieme
Original Publication: São Paulo.
مواضيع طبية MeSH: Brain Ischemia*/complications , Brain Ischemia*/diagnostic imaging , Foramen Ovale, Patent*/complications , Foramen Ovale, Patent*/diagnostic imaging , Ischemic Stroke* , Stroke*/diagnostic imaging , Stroke*/etiology, Humans ; Retrospective Studies ; Ultrasonography, Doppler, Transcranial
مستخلص: Background: Patent foramen ovale (PFO) has been considered a potential mechanism of embolic stroke of undetermined origin.
Objective: The aim of the present study was to identify the features of the right-to-left shunt (RLS) in patients with undetermined embolic ischemic stroke and compare them with those of patients with non-cardioembolic ischemic stroke.
Methods: A retrospective study was conducted with 168 patients with stroke and RLS separated into the following two groups: the undetermined embolic stroke group (UES group) and non-cardioembolic stroke group (NCES group). All patients were assessed by transcranial Doppler to evaluate the presence and quantification of microembolic signals (MES) at rest and under Valsalva maneuver.
Results: Of all patients evaluated in the current study, 96 were included in the UES group and 72 in the NCES group. In the UES group, 65 patients had RLS with ≥10 MES (67.7%), which was higher than that observed in the NCES group (51.4%, p=0.038). According to the moment of the cardiac cycle, 75 patients (78.1%) in the UES group had a positive test at rest compared to 42 (58.3%) in the NCES group (p=0.007).
Conclusions: The current study demonstrated that almost 70% of patients with undetermined embolic stroke and PFO presented a large RLS and more than 75% had RLS at rest. These findings suggest that the size of the shunt should be taken into account when evaluating whether PFO could be a possible mechanism underlying cryptogenic stroke.
التعليقات: Comment in: Arq Neuropsiquiatr. 2021 Oct;79(10):857-858. (PMID: 34706013)
تواريخ الأحداث: Date Created: 20211027 Date Completed: 20211108 Latest Revision: 20211108
رمز التحديث: 20240628
DOI: 10.1590/0004-282X-ANP-2020-0430
PMID: 34706014
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-4227
DOI:10.1590/0004-282X-ANP-2020-0430