دورية أكاديمية
Clinical and histopathological features of breast tumors in women: a cross-sectional study at three hospitals in the Kingdom of Saudi Arabia.
| العنوان: | Clinical and histopathological features of breast tumors in women: a cross-sectional study at three hospitals in the Kingdom of Saudi Arabia. |
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| المؤلفون: | Razik MA; General Surgery Department, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Alsubaie AM; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Alsetri HM; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Albassam KA; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Alkhurayyif AO; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Altamimi MM; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Alanazi SM; College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2021 Aug 24; Vol. 39, pp. 267. Date of Electronic Publication: 2021 Aug 24 (Print Publication: 2021). |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Breast Neoplasms/*pathology , Fibroadenoma/*pathology, Adolescent ; Adult ; Age Factors ; Aged ; Breast Neoplasms/epidemiology ; Carcinoma, Ductal, Breast/epidemiology ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Lobular/epidemiology ; Carcinoma, Lobular/pathology ; Carcinoma, Papillary/epidemiology ; Carcinoma, Papillary/pathology ; Cross-Sectional Studies ; Female ; Fibroadenoma/epidemiology ; Hospitals ; Humans ; Middle Aged ; Retrospective Studies ; Saudi Arabia/epidemiology ; Young Adult |
| مستخلص: | Introduction: there is a dearth of data on the epidemiology of breast tumors in the Kingdom of Saudi Arabia (KSA). This study aimed to determine the demographics, clinical patterns, and their association with histopathological types of breast tumors among females presently residing in KSA. Methods: a multi-centric, cross-sectional study including female patients with symptoms suggestive of breast tumor was conducted at three hospitals in KSA from February 2019 to February 2020. The patient´s electronic health records were used to collect information related to their demographics, clinical findings including comordbities and symptoms and investigations. Binary logistic regression models were used to determine factors associated with the breast tumors. Results: a total of 270 female patients were included in the study. The most frequently encountered symptom was a breast lump (95.9%, n = 259), followed by pain (18.9%, n = 51). More than half the population (53%, n = 143) had a histopathological diagnosis of fibroadenoma. Multivariate analysis revealed that patients > 46 years of age were less likely to present with fibroadenoma (AOR: 0.049 95% CI 0.02 - 0.15; p < 0.005). Those in the 31 - 45 years age group were less likely to present with ductal/lobular/papillary carcinomacompared to the less than 30 years group (AOR: 0.42, 95% CI 0.18 - 0.97; p = 0.04). Conclusion: in this population of Saudi women with symptoms suggestive of breast tumor, those aged less than 40 years were more likely to have a fibroadenoma whereas those above 40 years were more likely to have breast cancer. Competing Interests: The authors declare no competing interests. (Copyright: Mohamed Abdel Razik et al.) |
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| فهرسة مساهمة: | Keywords: Breast cancer; Saudi Arabia; ductal carcinoma; fibroadenoma; lobular carcinoma; tumors |
| تواريخ الأحداث: | Date Created: 20211028 Date Completed: 20211109 Latest Revision: 20220427 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8520403 |
| DOI: | 10.11604/pamj.2021.39.267.30341 |
| PMID: | 34707768 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2021.39.267.30341 |