دورية أكاديمية
Mechanical active compression-decompression versus standard mechanical cardiopulmonary resuscitation: A randomised haemodynamic out-of-hospital cardiac arrest study.
| العنوان: | Mechanical active compression-decompression versus standard mechanical cardiopulmonary resuscitation: A randomised haemodynamic out-of-hospital cardiac arrest study. |
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| المؤلفون: | Berve PO; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway; Air Ambulance Department, Division of Prehospital Services, Oslo University Hospital, Oslo, Norway; Department of Anaesthesiology, Oslo University Hospital, Oslo, Norway. Electronic address: peolbe@ous-hf.no., Hardig BM; Clinical Sciences, Helsingborg, Section II, Faculty of Medicine, Lund University, Sweden; Stryker/Jolife AB, Lund, Sweden., Skålhegg T; Air Ambulance Department, Division of Prehospital Services, Oslo University Hospital, Oslo, Norway., Kongsgaard H; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway., Kramer-Johansen J; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway; Air Ambulance Department, Division of Prehospital Services, Oslo University Hospital, Oslo, Norway., Wik L; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway; Air Ambulance Department, Division of Prehospital Services, Oslo University Hospital, Oslo, Norway; Department of Anaesthesiology, Oslo University Hospital, Oslo, Norway. |
| المصدر: | Resuscitation [Resuscitation] 2022 Jan; Vol. 170, pp. 1-10. Date of Electronic Publication: 2021 Oct 25. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier/north-Holland Biomedical Press Country of Publication: Ireland NLM ID: 0332173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1570 (Electronic) Linking ISSN: 03009572 NLM ISO Abbreviation: Resuscitation Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Limerick : Elsevier/north-Holland Biomedical Press Original Publication: London, Middlesex Pub. Co. |
| مواضيع طبية MeSH: | Cardiopulmonary Resuscitation*/methods , Out-of-Hospital Cardiac Arrest*/therapy , Thoracic Wall*, Adult ; Decompression ; Hemodynamics ; Humans ; Prospective Studies |
| مستخلص: | Background: Active compression-decompression cardiopulmonary resuscitation (ACD-CPR) utilises a suction cup to lift the chest-wall actively during the decompression phase (AD). We hypothesised that mechanical ACD-CPR (Intervention), with AD up to 30 mm above the sternal resting position, would generate better haemodynamic results than standard mechanical CPR (Control). Methods: This out-of-hospital adult non-traumatic cardiac arrest trial was prospective, block-randomised and non-blinded. We included intubated patients with capnography recorded during mechanical CPR. Exclusion criteria were pregnancy, prisoners, and prior chest surgery. The primary endpoint was maximum tidal carbon dioxide partial pressure (p Results: Of 221 enrolled patients, 210 were deemed eligible (Control 109, Intervention 101). The Control vs. Intervention results showed no significant differences for p Conclusions: Mechanical ACD-CPR provided similar haemodynamic results to standard mechanical CPR. The Intervention device did not consistently provide Complete AD. Clinical Trial Registration: ClinicalTrials.gov identifier (NCT number): NCT02479152. The Haemodynamic Effects of Mechanical Standard and Active Chest Compression-decompression During Out-of-hospital CPR. Competing Interests: Declaration of Competing Interest LW was PI in the Zoll Medical funded CIRC study and holds patents via Oslo University Hospital (Inven2). He is a member of the medical advisory board of Stryker/Physio-Control. At the time of the study, BMH was employed by Stryker/Jolife AB, which manufactures the LUCAS device, LIFEPAK 15 and CODE-STAT. In addition, JC did analysis and data work for the study that was funded by Stryker/Jolife AB. POB, TS, HK and JKJ declare no conflicts of interests. (Copyright © 2021 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: ACD-CPR; Active compression decompression; Capnography; Cardiac arrest; Cardiopulmonary resuscitation; Cerebral oximetry; ETCO(2); Haemodynamic; Invasive arterial blood pressure; Mechanical chest compression; NIRS; SctO(2); rSO(2) |
| سلسلة جزيئية: | ClinicalTrials.gov NCT02479152 |
| تواريخ الأحداث: | Date Created: 20211028 Date Completed: 20220324 Latest Revision: 20220324 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.resuscitation.2021.10.026 |
| PMID: | 34710550 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1873-1570 |
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| DOI: | 10.1016/j.resuscitation.2021.10.026 |