دورية أكاديمية
أعرض في EDS

The Role of Negative-Pressure Wound Therapy in Patients with Fracture-Related Infection: A Systematic Review and Critical Appraisal.

التفاصيل البيبلوغرافية
العنوان: The Role of Negative-Pressure Wound Therapy in Patients with Fracture-Related Infection: A Systematic Review and Critical Appraisal.
المؤلفون: Haidari S; Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, Netherlands., IJpma FFA; Department of Trauma Surgery, University Medical Center Groningen, Groningen, Netherlands., Metsemakers WJ; Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium., Maarse W; Department of Plastic, Reconstructive and Hand Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., Vogely HC; Department of Orthopedic Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., Ramsden AJ; Department of Plastic and Reconstructive Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Bone Infection Unit, Nuffield Orthopedic Centre, Oxford, UK., McNally MA; Bone Infection Unit, Nuffield Orthopedic Centre, Oxford, UK., Govaert GAM; Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
المصدر: BioMed research international [Biomed Res Int] 2021 Oct 19; Vol. 2021, pp. 7742227. Date of Electronic Publication: 2021 Oct 19 (Print Publication: 2021).
نوع المنشور: Journal Article; Meta-Analysis; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Hindawi Pub. Co.
مواضيع طبية MeSH: Negative-Pressure Wound Therapy/*methods , Surgical Wound Infection/*prevention & control, Bandages/adverse effects ; Fractures, Bone/surgery ; Humans ; Orthopedic Procedures/methods ; Suction ; Surgical Wound ; Surgical Wound Dehiscence/prevention & control ; Surgical Wound Infection/etiology ; Treatment Outcome ; Vacuum ; Wound Healing/physiology
مستخلص: Introduction: Fracture-related infection (FRI) is a severe musculoskeletal complication in orthopedic trauma surgery, causing challenges in bony and soft tissue management. Currently, negative-pressure wound therapy (NPWT) is often used as temporary coverage for traumatic and surgical wounds, also in cases of FRI. However, controversy exists about the impact of NPWT on the outcome in FRI, specifically on infection recurrence. Therefore, this systematic review qualitatively assesses the literature on the role of NPWT in the management of FRI.
Methods: A literature search of the PubMed, Embase, and Web of Science database was performed. Studies that reported on infection recurrence related to FRI management combined with NPWT were eligible for inclusion. Quality assessment was done using the PRISMA statement and the Newcastle-Ottawa Quality Assessment Scale.
Results: After screening and quality assessment of 775 unique identified records, eight articles could be included for qualitative synthesis. All eight studies reported on infection recurrence, which ranged from 2.8% to 34.9%. Six studies described wound healing time, varying from two to seven weeks. Four studies took repeated microbial swabs during subsequent vacuum dressing changes. One study reported newly detected pathogens in 23% of the included patients, and three studies did not find new pathogens.
Conclusion: This review provides an assessment of current literature on the role of NPWT in the management of soft tissue defects in patients with FRI. Due to the lack of uniformity in included studies, conclusions should be drawn with caution. Currently, there is no clear scientific evidence to support the use of NPWT as definitive treatment in FRI. At this stage, we can only recommend early soft tissue coverage (within days) with a local or free flap. NPWT may be safe for a few days as temporarily soft tissue coverage until definitive soft tissue management could be performed. However, comparative studies between NPWT and early wound closure in FRI patients are needed.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2021 Susan Haidari et al.)
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تواريخ الأحداث: Date Created: 20211101 Date Completed: 20220124 Latest Revision: 20231108
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8548908
DOI: 10.1155/2021/7742227
PMID: 34722772
قاعدة البيانات: MEDLINE
الوصف
تدمد:2314-6141
DOI:10.1155/2021/7742227