تقرير
Paraneoplastic Erythema Annulare Centrifugum Eruption (PEACE) Associated With Metastatic Colorectal Adenocarcinoma.
| العنوان: | Paraneoplastic Erythema Annulare Centrifugum Eruption (PEACE) Associated With Metastatic Colorectal Adenocarcinoma. |
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| المؤلفون: | Pitchford CA; Department of Dermatology, University of Missouri, Columbia, USA., R Shenk ME; Department of Dermatology, University of Missouri, Columbia, USA., Zurowski S; Department of Dermatology, University of Missouri, Columbia, USA., Smith EH; Department of Dermatology, University of Missouri, Columbia, USA. |
| المصدر: | Cureus [Cureus] 2021 Oct 02; Vol. 13 (10), pp. e18443. Date of Electronic Publication: 2021 Oct 02 (Print Publication: 2021). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
| مستخلص: | Erythema annulare centrifugum (EAC) is a figurate erythema presenting with annular, erythematous plaques with a trailing scale. It is considered a hypersensitivity reaction to a variety of antigens and is associated with multiple underlying causes including malignancy. Malignancy-associated EAC is termed paraneoplastic erythema annulare centrifugum eruption (PEACE). Although a specific etiology has yet to be elucidated, this form of EAC is likely to occur due to cytokine and/or antigen stimulation from an underlying malignancy. PEACE is primarily associated with lymphoproliferative disorders and rarely solid tumors. Our report discusses a case of PEACE associated with metastatic colorectal adenocarcinoma. On presentation to our clinic, the patient had developed a migratory annular eruption over a year. His review of symptoms was positive for signs of underlying malignancy, including weight loss and recent lower vertebral fracture. A biopsy of his annular lesion revealed a non-specific pityriasiform dermatitis. A vertebral biopsy uncovered a diagnosis of metastatic colorectal cancer. At that time, clinicopathologic correlation allowed us to reach the diagnosis of PEACE. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Pitchford et al.) |
| References: | Dermatol Online J. 2015 Dec 16;21(12):. (PMID: 26990337) Gastroenterology Res. 2010 Apr;3(2):96-98. (PMID: 27956993) Am J Clin Dermatol. 2012 Aug 1;13(4):239-46. (PMID: 22320680) J Eur Acad Dermatol Venereol. 2020 Oct;34(10):e617-e620. (PMID: 32311788) Am J Dermatopathol. 2003 Dec;25(6):451-62. (PMID: 14631185) |
| فهرسة مساهمة: | Keywords: annular erythema; cancer and oncology; clinical dermatology; cutaneous signs of disease; erythema and urticaria/figurate erythemas; paraneoplastic syndrome; pathology |
| تواريخ الأحداث: | Date Created: 20211105 Latest Revision: 20211106 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8559580 |
| DOI: | 10.7759/cureus.18443 |
| PMID: | 34737911 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2168-8184 |
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| DOI: | 10.7759/cureus.18443 |