دورية أكاديمية
Muscle-derived factors influencing bone metabolism.
| العنوان: | Muscle-derived factors influencing bone metabolism. |
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| المؤلفون: | Gries KJ; Program in Exercise & Sports Science, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Bone & Muscle Research Group, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Division of Biomedical Science, Marian University College of Osteopathic Medicine, 3200 Cold Spring Road, Indianapolis, IN 46222, USA. Electronic address: kgries@marian.edu., Zysik VS; Bone & Muscle Research Group, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Marian University College of Osteopathic Medicine, 3200 Cold Spring Road, Indianapolis, IN 46222, USA., Jobe TK; Program in Exercise & Sports Science, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA., Griffin N; Bone & Muscle Research Group, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Marian University College of Osteopathic Medicine, 3200 Cold Spring Road, Indianapolis, IN 46222, USA., Leeds BP; Bone & Muscle Research Group, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Division of Clinical Affairs, Marian University College of Osteopathic Medicine, 3200 Cold Spring Road, Indianapolis, IN 46222, USA., Lowery JW; Bone & Muscle Research Group, Marian University, 3200 Cold Spring Road, Indianapolis, IN 46222, USA; Division of Biomedical Science, Marian University College of Osteopathic Medicine, 3200 Cold Spring Road, Indianapolis, IN 46222, USA. |
| المصدر: | Seminars in cell & developmental biology [Semin Cell Dev Biol] 2022 Mar; Vol. 123, pp. 57-63. Date of Electronic Publication: 2021 Oct 30. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: England NLM ID: 9607332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-3634 (Electronic) Linking ISSN: 10849521 NLM ISO Abbreviation: Semin Cell Dev Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Academic Press Original Publication: London, UK : Academic Press, c1996- |
| مواضيع طبية MeSH: | Exercise*/physiology , Muscle, Skeletal*/metabolism, Bone and Bones ; Cytokines/metabolism |
| مستخلص: | A significant amount of attention has been brought to the endocrine-like function of skeletal muscle on various tissues, particularly with bone. Several lines of investigation indicate that the physiology of both bone and muscle systems may be regulated by a given stimulus, such as exercise, aging, and inactivity. Moreover, emerging evidence indicates that bone is heavily influenced by soluble factors derived from skeletal muscle (i.e., muscle-to-bone communication). The purpose of this review is to discuss the regulation of bone remodeling (formation and/or resorption) through skeletal muscle-derived cytokines (hereafter myokines) including the anti-inflammatory cytokine METRNL and pro-inflammatory cytokines (e.g., TNF-α, IL-6, FGF-2 and others). Our goal is to highlight possible therapeutic opportunities to improve muscle and bone health in aging. (Copyright © 2021 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Bone; Crosstalk; Exercise; Myokine; Skeletal muscle |
| المشرفين على المادة: | 0 (Cytokines) |
| تواريخ الأحداث: | Date Created: 20211110 Date Completed: 20220316 Latest Revision: 20220316 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.semcdb.2021.10.009 |
| PMID: | 34756782 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-3634 |
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| DOI: | 10.1016/j.semcdb.2021.10.009 |