دورية أكاديمية
أعرض في EDS

Outcomes of Penetrating Keratoplasty After Open Globe Injury.

التفاصيل البيبلوغرافية
العنوان: Outcomes of Penetrating Keratoplasty After Open Globe Injury.
المؤلفون: Li KX; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Durrani AF; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Zhou Y; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Zhao PY; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Tannen BL; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Mian SI; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Musch DC; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and.; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI., Zacks DN; Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and.
المصدر: Cornea [Cornea] 2022 Nov 01; Vol. 41 (11), pp. 1345-1352. Date of Electronic Publication: 2021 Nov 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8216186 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4798 (Electronic) Linking ISSN: 02773740 NLM ISO Abbreviation: Cornea Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, N.Y. : Masson Pub. USA, c1982-
مواضيع طبية MeSH: Endophthalmitis*/etiology , Eye Injuries*/etiology , Retinal Detachment*, Female ; Graft Survival ; Humans ; Keratoplasty, Penetrating/adverse effects ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Visual Acuity
مستخلص: Purpose: The purpose of this study was to investigate the clinical features, surgical outcomes, and prognostic factors of penetrating keratoplasty (PKP) after open globe injury (OGI).
Methods: A retrospective review of all patients treated for OGI between January 2000 and July 2017 was conducted. Demographic, preoperative, perioperative, and postoperative data were collected for those who underwent PKP after OGI. The predictive value of each preoperative variable on graft failure was assessed using univariate and multivariable Cox proportional hazards models, and the predictive value of variables on post-PKP visual outcome was assessed using both univariate and multivariable logistic regression models. All eyes that underwent PKP after OGI were included unless they had less than 365 days of follow-up.
Results: Forty-six eyes that underwent PKP met inclusion criteria. The median age was 46 years (interquartile range = 23.00-61.25), median follow-up was 78.5 months (interquartile range = 38.63-122.02), and 37 of 46 subjects (80.4%) were male. The observed 1- and 5-year graft survival estimates were 80.4% and 41.7%, respectively. Factors statistically associated with graft failure in multivariable analyses were rejection episode, hazard ratio (HR) = 3.29; retinal detachment (RD), HR = 3.47; and endophthalmitis, HR = 6.27. Fifteen of 42 eyes (35.7%) regained ambulatory vision (20/200 or better). The strongest predictors of vision worse than 20/200 at the last follow-up were RD, odds ratio (OR) = 43.88; graft rejection, OR = 12.42; and injury outside the workplace, OR = 25.05.
Conclusions: Despite a high graft survival at 1 year, most of the patients did not regain ambulatory vision. Graft rejection, RD, and endophthalmitis were risk factors for graft failure. These factors should be considered when counseling patients regarding PKP after OGI.
Competing Interests: The authors have no funding or conflicts of interest to disclose.
(Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.)
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تواريخ الأحداث: Date Created: 20211111 Date Completed: 20221013 Latest Revision: 20230912
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9555754
DOI: 10.1097/ICO.0000000000002918
PMID: 34759204
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-4798
DOI:10.1097/ICO.0000000000002918