دورية أكاديمية
Consequences and implications of the coronavirus disease (COVID-19) on pregnancy and newborns: A comprehensive systematic review and meta-analysis.
العنوان: | Consequences and implications of the coronavirus disease (COVID-19) on pregnancy and newborns: A comprehensive systematic review and meta-analysis. |
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المؤلفون: | de Medeiros KS; Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.; Department of Nursing, Centro Universitário do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Sarmento ACA; Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil., Costa APF; Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil., Macêdo LTA; Department of Nursing, Centro Universitário do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., da Silva LAS; Department of Nursing, Centro Universitário do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., de Freitas CL; Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil., Simões ACZ; Department of Obstetrics and Gynecology, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil., Gonçalves AK; Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.; Department of Obstetrics and Gynecology, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil. |
المصدر: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2022 Mar; Vol. 156 (3), pp. 394-405. Date of Electronic Publication: 2021 Nov 19. |
نوع المنشور: | Journal Article; Meta-Analysis; Review; Systematic Review |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0210174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3479 (Electronic) Linking ISSN: 00207292 NLM ISO Abbreviation: Int J Gynaecol Obstet Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2017- : Malden, MA : Wiley Original Publication: [New York, NY] Hoeber Medical Division, Harper & Row, [c1969- |
مواضيع طبية MeSH: | Abortion, Spontaneous* , COVID-19* , Pregnancy Complications, Infectious*/epidemiology , Premature Birth*/epidemiology, Female ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Outcome/epidemiology ; Pregnant Women ; SARS-CoV-2 |
مستخلص: | Background: Pregnant patients are potentially vulnerable to COVID-19. Objectives: To clarify the clinical features of COVID-19 and analyze maternal/fetal morbidity and mortality and the obstetric and neonatal outcomes of pregnant patients. Search Strategy: Embase, PubMed, Web of Science, CINAHAL, LILACS, Google Scholar, and Scopus. Selection Criteria: Articles published from December 2019 to February 2021. Data Collection and Analysis: The reviewers extracted relevant data from the full-text. Data synthesis was performed using the R-4.1.0 Project for Statistical Computing for Windows. The meta-analysis of the included studies was carried out using the random-effects model (DerSimonian and Laird). Heterogeneity was measured using I 2 analysis. Results: A total of 70 studies included 10 047 pregnant women with COVID-19, of whom 71.6% were in their third trimester. The most common symptoms were fever, cough, chest pain, dyspnea, and fatigue. Most newborns were delivered preterm (24%, 95% confidence interval [CI] 0.17-0.34, I 2 = 93%) and via cesarean delivery (42%, 95% CI 0.38-0.47, I 2 = 92%). There were 108 maternal mortalities (2%, 95% CI 0.01-0.03, I 2 = 54%) and 50 abortions (5%, 95% CI 0.03-0.09, I 2 = 73%). The neonatal outcomes included fetal distress (11%, 95% CI 0.06-0.19, I 2 = 91%), birth weight (15%, 95% CI 0.10-0.21, I 2 = 76%), APGAR <7 (19%, 95% CI 0.12-0.28, I 2 = 43%), admission to the neonatal intensive care unit (28%, 95% CI 0.17-0.43, I 2 = 90%), and fetal mortality (2%, 95% CI 0.01-0.03, I 2 = 46%). Conclusion: There was no evidence of severe acute respiratory syndrome coronavirus-2 in the placenta, breast milk, umbilical cord, and amniotic fluid of pregnant patients. PROSPERO registration number: CRD42020181519. (© 2021 International Federation of Gynecology and Obstetrics.) |
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فهرسة مساهمة: | Keywords: COVID-19; coronavirus disease 2019; obstetrics; pregnancy |
تواريخ الأحداث: | Date Created: 20211111 Date Completed: 20220208 Latest Revision: 20220716 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC9087607 |
DOI: | 10.1002/ijgo.14015 |
PMID: | 34762735 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1879-3479 |
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DOI: | 10.1002/ijgo.14015 |