دورية أكاديمية
أعرض في EDS

Potential of Malawi's medicinal plants in Covid-19 disease management: A review.

التفاصيل البيبلوغرافية
العنوان: Potential of Malawi's medicinal plants in Covid-19 disease management: A review.
المؤلفون: Chikowe I; Pharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences., Mtewa AG; Chemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Thyolo, Malawi., Tembo D; The Polytechnic, University of Malawi, Blantyre, Malawi/Malawi University of Business and Applied Sciences., Smith D; Pharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences., Ibrahim E; The Polytechnic, University of Malawi, Blantyre, Malawi/Malawi University of Business and Applied Sciences., Mwamatope B; University of Livingstonia, Rumphi, Malawi., Nkhungulu J; Pharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences., Kumpalume P; Pharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences., Maroyi A; University of Fort Hare, Alice, South Africa.
المصدر: Malawi medical journal : the journal of Medical Association of Malawi [Malawi Med J] 2021 Jun; Vol. 33 (2), pp. 85-107.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Published by Montfort Press for the Medical Association of Malawi Country of Publication: Malawi NLM ID: 9500170 Publication Model: Print Cited Medium: Internet ISSN: 1995-7270 (Electronic) Linking ISSN: 19957262 NLM ISO Abbreviation: Malawi Med J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Lilongwe, Malawi : Published by Montfort Press for the Medical Association of Malawi, [1990-
مواضيع طبية MeSH: COVID-19* , Plants, Medicinal*, Antiviral Agents/therapeutic use ; Humans ; Malawi ; Phytochemicals ; SARS-CoV-2
مستخلص: The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered an international pandemic that has led to significant public health problems. To date, limited evidence exists to suggest that drugs are effective against the disease. As possible treatments are being investigated, herbal medicines have shown potential for producing novel antiviral agents for the COVID-19 disease.
Aim: This review explored the potential of Malawi's traditional medicinal plants for the management of COVID-19.
Methods: The authors searched on PubMed and Google scholar for medicinal plants that are used in Malawi and published in openly available peer reviewed journals. Plants linked with antiviral treatment, anti-COVID-19 activity or COVID-19 symptoms management were targeted. These included activity against pneumonia, inflammation, cough, difficulty in breathing, pain/aches, fever, diarrhoea, rheumatism, fatigue, asthma, immunocompromised and cardiovascular diseases.
Results: 11 studies were found with 306 plant species. 127 plant species had at least one COVID-19 related pharmacological activity. Of these plant species, the number of herbal entities used for each indication was: pain/aches (87), fever (2), pneumonia (9), breathing/asthma problems (5), coughing (11), diarrhoea (1), immunosuppression (8), blood issues (10), fatigue (2), heart problems (11), inflammation (8), rheumatism (10) and viral diseases (12). Thirty (30) species were used for more than one disease and Azedarachta indica topped the list (6 of the 13 COVID-19 related diseases). The majority of the species had phytochemicals known to have antiviral activity or mechanisms of actions linked to COVID-19 and consequent diseases' treatment pathways.
Conclusion: Medicinal plants are a promising source of compounds that can be used for drug development of COVID-19 related diseases. This review highlights potential targets for the World Health Organization and other research entities to explore in order to assist in controlling the pandemic.
(© 2021 The College of Medicine and the Medical Association of Malawi.)
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فهرسة مساهمة: Keywords: corona virus; drug development; herbal products; screening; traditional medicine
المشرفين على المادة: 0 (Antiviral Agents)
0 (Phytochemicals)
تواريخ الأحداث: Date Created: 20211115 Date Completed: 20211118 Latest Revision: 20240404
رمز التحديث: 20240404
مُعرف محوري في PubMed: PMC8560350
DOI: 10.4314/mmj.v33i2.4
PMID: 34777704
قاعدة البيانات: MEDLINE
الوصف
تدمد:1995-7270
DOI:10.4314/mmj.v33i2.4