Left ventricular function and cardiac valvar annular dimensions among children with sickle cell anemia compared to those with hemoglobin AA type in Enugu, Nigeria.

التفاصيل البيبلوغرافية
العنوان:	Left ventricular function and cardiac valvar annular dimensions among children with sickle cell anemia compared to those with hemoglobin AA type in Enugu, Nigeria.
المؤلفون:	Chinawa JM; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Nigeria., Chinawa AT; Consultant Community Physician and Lecturer Enugu state University Teaching hospital, Enugu State., Ossai EN; Department of community Medicine College of Health Sciences Ebonyi State University Abakaliki, Nigeria., Chukwu BF; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Nigeria., Ndu IK; Department of Paediatrics, Enugu state University Teaching hospital, Enugu State., Asinobi IN; Department of Paediatrics, Enugu state University Teaching hospital, Enugu State.
المصدر:	Malawi medical journal : the journal of Medical Association of Malawi [Malawi Med J] 2021 Jun; Vol. 33 (2), pp. 127-134.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Published by Montfort Press for the Medical Association of Malawi Country of Publication: Malawi NLM ID: 9500170 Publication Model: Print Cited Medium: Internet ISSN: 1995-7270 (Electronic) Linking ISSN: 19957262 NLM ISO Abbreviation: Malawi Med J Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Lilongwe, Malawi : Published by Montfort Press for the Medical Association of Malawi, [1990-
مواضيع طبية MeSH:	Anemia, Sickle Cell* , Ventricular Function, Left*, Cross-Sectional Studies ; Hemoglobin A ; Humans ; Nigeria ; Prospective Studies
مستخلص:	Background: Enumerating the relationship between cardiac structures, function and chamber sizes in children with sickle cell anemia would help in delineating some cardiovascular abnormalities which will aid the Pediatric cardiologist and the cardiac surgeons in a number of decision-making situations. Objectives: The objectives of this study are to assess the dimension of cardiac structures and left ventricular function in children with sickle cell anemia in steady state and controls using echocardiography. Methods: A cross-sectional prospective study that assessed cardiac structures and left ventricular function among fifty-one children with sickle cell anemia (HBSS) and compared with fifty children with HB AA type serving as controls. Results: A significant high proportion of children with sickle cell anemia had abnormal Valvar dimension and left ventricular function above two standard deviations (2-SD) from the mean of the standard population compared to the control group, showing a statistically significant difference (χ2 = 10.42, p= 0.001).All the mean annular valves diameter, left ventricular internal dimension in systole and diastole, inter-sinus distance diameter and sinu-tubular junction diameter are higher in children with sickle cell anemia than controls and this is statistically significant. (p<0.005). Conclusion: This result shows that children with sickle cell anemia have increased valvar size diameter compared with those with normal hemoglobin type. A significantly higher proportion of respondents in type SS group had abnormal left ventricular systolic and diastolic dysfunction when compared with those in type AA group. (© 2021 The College of Medicine and the Medical Association of Malawi.)
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فهرسة مساهمة:	Keywords: cardiac structures; children; echocardiography; sickle cell anemia
المشرفين على المادة:	37248-06-9 (hemoglobin AA) 9034-51-9 (Hemoglobin A)
تواريخ الأحداث:	Date Created: 20211115 Date Completed: 20211223 Latest Revision: 20211223
رمز التحديث:	20231215
مُعرف محوري في PubMed:	PMC8560357
DOI:	10.4314/mmj.v33i2.8
PMID:	34777708
قاعدة البيانات:	MEDLINE

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الوصف
تدمد:	1995-7270
DOI:	10.4314/mmj.v33i2.8