دورية أكاديمية
Surgical treatment of multiple large tuberous xanthomas in familial hypercholesterolemia: A case report.
| العنوان: | Surgical treatment of multiple large tuberous xanthomas in familial hypercholesterolemia: A case report. |
|---|---|
| المؤلفون: | Dung PTV; Department of Plastic Surgery, Hanoi Medical University, No.1 Ton That Tung Street, Hanoi, Viet Nam; Department of Plastic Reconstructive and Aesthetic Surgery, Bach Mai Hospital, No.78 Giai Phong Street, Hanoi, Viet Nam; Department of Plastic Reconstructive and Aesthetic Surgery, Hanoi Medical University Hospital, No.1 Ton That Tung Street, Hanoi, Viet Nam. Electronic address: phamvietdung@hmu.edu.vn., Son TT; Department of Plastic Surgery, Hanoi Medical University, No.1 Ton That Tung Street, Hanoi, Viet Nam; Department of Plastic Reconstructive and Aesthetic Surgery, Bach Mai Hospital, No.78 Giai Phong Street, Hanoi, Viet Nam. Electronic address: tranthietson@hmu.edu.vn., Thuy TTH; Department of Plastic Surgery, Hanoi Medical University, No.1 Ton That Tung Street, Hanoi, Viet Nam; Department of Plastic Reconstructive and Aesthetic Surgery, Bach Mai Hospital, No.78 Giai Phong Street, Hanoi, Viet Nam. Electronic address: tahongthuy@hmu.edu.vn., Chien VH; Department of Plastic Reconstructive and Aesthetic Surgery, Bach Mai Hospital, No.78 Giai Phong Street, Hanoi, Viet Nam. Electronic address: chienyhn@gmail.com., Duy TT; Department of Plastic Surgery, Hanoi Medical University, No.1 Ton That Tung Street, Hanoi, Viet Nam. Electronic address: theduytruonghmu@gmail.com., Le Van Huy; Department of Plastic Surgery, Hanoi Medical University, No.1 Ton That Tung Street, Hanoi, Viet Nam. Electronic address: h8le.md@gmail.com. |
| المصدر: | International journal of surgery case reports [Int J Surg Case Rep] 2021 Dec; Vol. 89, pp. 106596. Date of Electronic Publication: 2021 Nov 12. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101529872 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2210-2612 (Print) Linking ISSN: 22102612 NLM ISO Abbreviation: Int J Surg Case Rep Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Amsterdam] : Elsevier B.V. |
| مستخلص: | Introduction and Importance: Xanthomas are a rare condition with the appearance of exogenous masses on the body, and it is common in patients with familial hypercholesterolemia (FH). For multiple large xanthomas, surgical excision is optimal to improve the patient's quality of life. Case Presentation: A 34-year-old male patient presented with multiple large tuberous xanthomas related to FH. There were 15 masses in different body parts, including the dorsum of the hands, elbows, buttocks, feet, and Achille's tendon. The largest masses in the buttocks measured 8 × 8 × 5 cm. Surgical removal of 13 masses was carried out in combination with medical treatment. The skin incision was oval around the circumference of masses with the longitudinal axis parallel to the Langer's line. Skin defects were closed directly or dissected on both sides of the incision to reduce tension. Wound healing was normal. After 1.5 months, there was no recurrence of xanthomas. Clinical Discussion: Surgical treatment easily removes the entire tuberous xanthomas. The healing process is completely normal. Resection should be indicated for tuberous xanthomas that cause negative functional and aesthetic effects. Besides, lipid-lowering therapy is necessary to prevent tuberous xanthomas recurrence as well as premature coronary artery diseases. Conclusion: Surgical treatment of patients with multiple large tuberous xanthomas related to familial hypercholesterolemia was performed safely and successfully. After 1.5 months of follow-up, the wound healed well and no recurrence of xanthomas was detected. We recommend that a further study is needed to investigate post-treatment recurrence for multiple large xanthomas. (Copyright © 2021. Published by Elsevier Ltd.) |
| فهرسة مساهمة: | Keywords: Case report; Familial hypercholesterolemia; Tuberous xanthoma |
| تواريخ الأحداث: | Date Created: 20211115 Latest Revision: 20211221 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8599109 |
| DOI: | 10.1016/j.ijscr.2021.106596 |
| PMID: | 34781245 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 2210-2612 |
|---|---|
| DOI: | 10.1016/j.ijscr.2021.106596 |