دورية أكاديمية
Characterization of electrocorticographic, electromyographic and electrocardiographic recordings after the use of caffeine in Wistar rats.
| العنوان: | Characterization of electrocorticographic, electromyographic and electrocardiographic recordings after the use of caffeine in Wistar rats. |
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| المؤلفون: | Cabral DAC; Universidade Federal do Pará, Belém, PA, Brazil., Campos FMS; Universidade Federal do Pará, Belém, PA, Brazil., Silva MCPD; Universidade Federal do Pará, Belém, PA, Brazil., Medeiros JPDV; Universidade Federal do Pará, Belém, PA, Brazil., Batista PDS; Universidade Federal do Pará, Belém, PA, Brazil., Jardim GC; Universidade Federal do Pará, Belém, PA, Brazil., Machado JLP; Universidade Federal do Pará, Belém, PA, Brazil., Cabral LGC; Universidade Federal do Pará, Belém, PA, Brazil., Mello VJ; Universidade Federal do Pará, Belém, PA, Brazil., Hamoy M; Universidade Federal do Pará, Belém, PA, Brazil. |
| المصدر: | Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2021 Nov 15; Vol. 19, pp. eAO6417. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021). |
| نوع المنشور: | Journal Article |
| اللغة: | English; Portuguese |
| بيانات الدورية: | Publisher: Instituto de Ensino e Pesquisa Albert Einstein Country of Publication: Brazil NLM ID: 101281800 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6385 (Electronic) Linking ISSN: 16794508 NLM ISO Abbreviation: Einstein (Sao Paulo) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, SP : Instituto de Ensino e Pesquisa Albert Einstein |
| مواضيع طبية MeSH: | Caffeine*/pharmacology , Muscle Contraction*, Animals ; Electrocardiography ; Male ; Muscle, Skeletal ; Rats ; Rats, Wistar |
| مستخلص: | Objective: To describe electrocorticographic, electromyographic and electrocardiographic profiles to report the electrophysiological effects of caffeine in Wistar rats. Methods: Male adult Wistar rats weighing 230g to 250g were used. Rats were allocated to one of two groups, as follows: Group 1, Control, intraperitoneal injection of 0.9% saline solution (n=27); and Group 2, treated with intraperitoneal injection of caffeine (50mg/kg; n=27). The rats were submitted to electrocorticographic, electromyographic and electrocardiographic assessment. Results: Brain oscillations (delta, theta, alpha, beta and gamma) in the frequency range up to 40Hz varied after caffeine administration to rats. Powers in delta and theta oscillations ranges were preponderant. The contractile force of the skeletal striated and cardiac muscles increased. Electrocardiogram analysis revealed shorter RR, QRS and QT intervals under the effect of caffeine. Conclusion: In the central nervous system, there was an increase in the delta, theta and alpha amplitude spectrum, which are related to memory encoding and enhanced learning. With regard to skeletal muscle, increased contraction of the gastrocnemius muscle was demonstrated, a clear indication of how caffeine can be used to enhance performance of some physical activities. Electrocardiographic changes observed after caffeine administration are primarily related to increased heart rate and energy consumption. |
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| المشرفين على المادة: | 3G6A5W338E (Caffeine) |
| تواريخ الأحداث: | Date Created: 20211117 Date Completed: 20211118 Latest Revision: 20211120 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC8577317 |
| DOI: | 10.31744/einstein_journal/2021AO6417 |
| PMID: | 34787292 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2317-6385 |
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| DOI: | 10.31744/einstein_journal/2021AO6417 |