دورية أكاديمية
Prevalence of severe adverse events among health professionals after receiving the first dose of the ChAdOx1 nCoV-19 coronavirus vaccine (Covishield) in Togo, March 2021.
| العنوان: | Prevalence of severe adverse events among health professionals after receiving the first dose of the ChAdOx1 nCoV-19 coronavirus vaccine (Covishield) in Togo, March 2021. |
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| المؤلفون: | Konu YR; Public Health Department, University of Lomé, Lomé, Togo.; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo., Gbeasor-Komlanvi FA; Public Health Department, University of Lomé, Lomé, Togo.; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo., Yerima M; Ministry of Health and Public Hygiene, Pharmacovigilance Department, Lomé, Togo., Sadio AJ; Public Health Department, University of Lomé, Lomé, Togo.; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo., Tchankoni MK; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo., Zida-Compaore WIC; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo., Nayo-Apetsianyi J; Ministry of Health and Public Hygiene, Lomé, Togo., Afanvi KA; Public Health Department, University of Lomé, Lomé, Togo.; Ministry of Health and Public Hygiene, Lomé, Togo., Agoro S; Public Health Department, University of Lomé, Lomé, Togo.; Ministry of Health and Public Hygiene, Lomé, Togo., Salou M; Laboratory of Molecular Biology and Immunology (BIOLIM), University of Lomé, Lomé, Togo., Landoh DE; World Health Organization (WHO), Country Office of Togo, Lomé, Togo., Nyansa AB; Ministry of Health and Public Hygiene, Pharmacovigilance Department, Lomé, Togo., Boko E; Faculty of Health Sciences, University of Lomé, Lomé, Togo., Mijiyawa M; Ministry of Health and Public Hygiene, Lomé, Togo.; Faculty of Health Sciences, University of Lomé, Lomé, Togo., Ekouevi DK; Public Health Department, University of Lomé, Lomé, Togo. didier.ekouevi@gmail.com.; African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo. didier.ekouevi@gmail.com.; Inserm Center, Institute of Public Health and Development and University of Bordeaux, 1219, Bordeaux, France. didier.ekouevi@gmail.com. |
| المصدر: | Archives of public health = Archives belges de sante publique [Arch Public Health] 2021 Nov 24; Vol. 79 (1), pp. 207. Date of Electronic Publication: 2021 Nov 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 9208826 Publication Model: Electronic Cited Medium: Print ISSN: 0778-7367 (Print) Linking ISSN: 07787367 NLM ISO Abbreviation: Arch Public Health Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: <2011-> : London : BioMed Central Original Publication: Brussels : "Archives belges de médecine sociale" asbl., [1990- |
| مستخلص: | Background: The coronavirus disease 2019 (COVID-19) vaccines can cause adverse events that can lead to vaccine hesitancy. This study aims at estimating the prevalence of severe adverse events (SAEs) and their associated factors among health professionals vaccinated with ChAdOx1 nCoV-19 vaccine in Togo. Methods: A cross-sectional study was conducted from March 13th to 19th, 2021 in Togo among health professionals who received the first dose of the vaccine. An online self-administered questionnaire was used to collect sociodemographic and vaccination data. SAEs were defined as one resulting in hospitalization, medical consultation, or inability to work the day following the administration of the vaccine. Data analysis were performed using R© 4.0.1 software, and a 5% significance level was considered. Results: A total of 1,639 health professionals (70.2% male) with a median age of 32 (interquartile range: 27-40) were enrolled. At least one adverse event was reported among 71.6% of participants (95% CI = [69.3-73.8]). The most commonly reported adverse events were injection site pain (91.0%), asthenia (74.3%), headache (68.7%), soreness (55.0%), and fever (47.5%). An increased libido was also reported in 3.0% of participants. Of the participants who experienced adverse events, 18.2% were unable to go to work the day after vaccination, 10.5% consulted a medical doctor, and 1.0% were hospitalized. The SAEs' prevalence was 23.8% (95% CI = [21.8-25.9]). Being <30 years (AOR = 5.54; p<0.001), or 30-49 years (AOR = 3.62; p<0.001) and being female (AOR = 1.97; p<0.001) were associated with SAEs. Conclusions: High prevalence of SAEs have been observed in health professionals in Togo after ChAdOx1 nCoV-19 vaccination especially in young people and females. However, these data are reassuring as they inform on COVID-19 vaccines' SAE management. Systematic prescription of antalgics or antipyretics could be proposed to young people who get vaccinated. (© 2021. The Author(s).) |
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| معلومات مُعتمدة: | 001 International WHO_ World Health Organization |
| فهرسة مساهمة: | Keywords: Adverse event; COVID-19; ChAdOx1 nCoV-19; Health professionals; Togo; Vaccine |
| تواريخ الأحداث: | Date Created: 20211125 Latest Revision: 20220126 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8611394 |
| DOI: | 10.1186/s13690-021-00741-x |
| PMID: | 34819146 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0778-7367 |
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| DOI: | 10.1186/s13690-021-00741-x |