دورية أكاديمية
أعرض في EDS

Evaluation of Identification and Susceptibility for Candida Spp. Isolated Directly from Positive Blood Culture Bottles.

التفاصيل البيبلوغرافية
العنوان: Evaluation of Identification and Susceptibility for Candida Spp. Isolated Directly from Positive Blood Culture Bottles.
المؤلفون: Celestino de Souza Â; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Goldani LZ; Infectious Diseases Section, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Roesch EW; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Lutz L; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Barth PO; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., André de Souza Sampaio P; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Aquino VR; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil., Pereira DC; Microbiology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande do Sul, Porto Alegre, Brazil.
المصدر: International journal of microbiology [Int J Microbiol] 2021 Nov 16; Vol. 2021, pp. 9364231. Date of Electronic Publication: 2021 Nov 16 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101516125 Publication Model: eCollection Cited Medium: Print ISSN: 1687-918X (Print) NLM ISO Abbreviation: Int J Microbiol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Nasr City, Cairo] : Hindawi Pub. Corp.
مستخلص: Determination of the susceptibility profile of isolates of Candida from blood culture bottles is extremely important for correctly guiding patient pharmacotherapy. The aim of this study was to compare the results of analysis of Candida isolated directly from blood culture bottles by the VITEK MS MALDI-TOF identification system and the fluconazole disk diffusion assay with those of standard identification methods. Testing directly from the bottle allowed results 24 to 48 hours quicker than the standard method. There was a categorical agreement of 51.64% (47 of 91 samples) between the results of analysis directly from the bottle and analysis by the standard method. Regarding species identification, there was 96.15% agreement for Candida parapsilosis (25 of 26 samples). Categorical agreement between the rapid and standard disk diffusion methods was 95%, and the agreement between the rapid disk diffusion method and the broth microdilution method was 97%. Only minor errors in the rapid method were observed: 3 (5%) in the standard disk diffusion method and 2 (3%) in the broth microdilution method. Our study concluded that the rapid disk diffusion method for fluconazole is a fast, easy, reproducible, and consistent method. Its timely implementation for testing antifungal agents in the clinical microbiology laboratory can help reduce profile release times, thus helping to determine the most appropriate antifungal treatment.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2021 Ândrea Celestino de Souza et al.)
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تواريخ الأحداث: Date Created: 20211126 Latest Revision: 20211127
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8610690
DOI: 10.1155/2021/9364231
PMID: 34824584
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-918X
DOI:10.1155/2021/9364231