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Acute graft rejection in a high-risk corneal transplant following COVID-19 vaccination: A case report.

التفاصيل البيبلوغرافية
العنوان: Acute graft rejection in a high-risk corneal transplant following COVID-19 vaccination: A case report.
المؤلفون: Parmar DP; Department of Cornea, M and J Institute of Ophthalmology, (Government Eye Hospital), B. J. Medical College, Ahmedabad, Gujarat, India., Garde PV; Department of Cornea, M and J Institute of Ophthalmology, (Government Eye Hospital), B. J. Medical College, Ahmedabad, Gujarat, India., Shah SM; Department of Cornea, M and J Institute of Ophthalmology, (Government Eye Hospital), B. J. Medical College, Ahmedabad, Gujarat, India., Bhole PK; Department of Cornea, M and J Institute of Ophthalmology, (Government Eye Hospital), B. J. Medical College, Ahmedabad, Gujarat, India.
المصدر: Indian journal of ophthalmology [Indian J Ophthalmol] 2021 Dec; Vol. 69 (12), pp. 3757-3758.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Mumbai : Medknow Publications
Original Publication: Bombay : All-India Ophthalmological Society
مواضيع طبية MeSH: COVID-19* , Corneal Diseases*/surgery , Corneal Transplantation*, COVID-19 Vaccines ; Graft Rejection/diagnosis ; Graft Rejection/prevention & control ; Humans ; Keratoplasty, Penetrating/adverse effects ; SARS-CoV-2 ; Vaccination/adverse effects
مستخلص: As COVID-19 vaccination is being undertaken all over the world, its side effects are materializing slowly. One such emerging side effect is acute graft rejection in corneal transplant (CT) cases post COVID-19 vaccination. We report a case of left eye (LE) repeat penetrating keratoplasty presenting with diminished vision in LE within 2 days of COVID-19 vaccination (ChAdOx1 nCoV-19 Corona Virus Vaccine Recombinant, COVISHIELD™). The patient was diagnosed with acute graft rejection post vaccination and was treated with topical and systemic immunosuppression therapy with successful outcome in terms improvement of visual acuity and corneal graft clarity. Timely presentation, diagnosis, and management may help to survive acute rejection episodes post vaccination.
Competing Interests: None
References: Surv Ophthalmol. 2017 Nov - Dec;62(6):816-827. (PMID: 28012874)
Cornea. 2021 Dec 1;40(12):1541-1547. (PMID: 34749379)
Indian J Ophthalmol. 2021 Jul;69(7):1953-1954. (PMID: 34146066)
Am J Ophthalmol. 1996 Jun;121(6):708-9. (PMID: 8644815)
Cornea. 1994 Sep;13(5):383-8. (PMID: 7995059)
Br J Ophthalmol. 2006 Jul;90(7):925. (PMID: 16782961)
J Fr Ophtalmol. 2021 Oct;44(8):e445-e447. (PMID: 34281760)
Eye (Lond). 2021 Aug 23;:. (PMID: 34426655)
Br J Ophthalmol. 2021 Jul;105(7):893-896. (PMID: 33910885)
Am J Ophthalmol. 1988 Nov 15;106(5):575-8. (PMID: 3056015)
فهرسة مساهمة: Keywords: COVID-19 vaccination; graft rejection; high-risk corneal transplant; repeat penetrating keratoplasty
المشرفين على المادة: 0 (COVID-19 Vaccines)
تواريخ الأحداث: Date Created: 20211127 Date Completed: 20211203 Latest Revision: 20220308
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8837359
DOI: 10.4103/ijo.IJO_2515_21
PMID: 34827040
قاعدة البيانات: MEDLINE
الوصف
تدمد:1998-3689
DOI:10.4103/ijo.IJO_2515_21