دورية أكاديمية
أعرض في EDS

Lipid Transfer Proteins (LTPs)-Structure, Diversity and Roles beyond Antimicrobial Activity.

التفاصيل البيبلوغرافية
العنوان: Lipid Transfer Proteins (LTPs)-Structure, Diversity and Roles beyond Antimicrobial Activity.
المؤلفون: Amador VC; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Santos-Silva CAD; Department of Advanced Diagnostics, Institute for Maternal and Child Health-IRCCS, Burlo Garofolo, 34100 Trieste, Italy., Vilela LMB; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Oliveira-Lima M; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., de Santana Rêgo M; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Roldan-Filho RS; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Oliveira-Silva RL; General Microbiology Laboratory, Agricultural Science Campus, Universidade Federal do Vale do São Francisco, Petrolina 56300-990, Brazil., Lemos AB; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., de Oliveira WD; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Ferreira-Neto JRC; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil., Crovella S; Department of Biological and Environmental Sciences, College of Arts and Science, Qatar University, Doha 1883, Qatar., Benko-Iseppon AM; Bioscience Centre, Genetics Department, Universidade Federal de Pernambuco, Recife 50670-420, Brazil.
المصدر: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2021 Oct 21; Vol. 10 (11). Date of Electronic Publication: 2021 Oct 21.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101637404 Publication Model: Electronic Cited Medium: Print ISSN: 2079-6382 (Print) Linking ISSN: 20796382 NLM ISO Abbreviation: Antibiotics (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2012-
مستخلص: Lipid transfer proteins (LTPs) are among the most promising plant-exclusive antimicrobial peptides (AMPs). They figure among the most challenging AMPs from the point of view of their structural diversity, functions and biotechnological applications. This review presents a current picture of the LTP research, addressing not only their structural, evolutionary and further predicted functional aspects. Traditionally, LTPs have been identified by their direct isolation by biochemical techniques, whereas omics data and bioinformatics deserve special attention for their potential to bring new insights. In this context, new possible functions have been identified revealing that LTPs are actually multipurpose, with many additional predicted roles. Despite some challenges due to the toxicity and allergenicity of LTPs, a systematic review and search in patent databases, indicate promising perspectives for the biotechnological use of LTPs in human health and also plant defense.
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فهرسة مساهمة: Keywords: bioinformatics; cationic peptides; omics databases; prediction directed analysis
تواريخ الأحداث: Date Created: 20211127 Latest Revision: 20240404
رمز التحديث: 20240404
مُعرف محوري في PubMed: PMC8615156
DOI: 10.3390/antibiotics10111281
PMID: 34827219
قاعدة البيانات: MEDLINE
الوصف
تدمد:2079-6382
DOI:10.3390/antibiotics10111281