دورية أكاديمية
أعرض في EDS

Glutathione Peroxidase in Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Glutathione Peroxidase in Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.
المؤلفون: Zinellu E; Clinical and Interventional Pulmonology, University Hospital Sassari (AOU), 07100 Sassari, Italy., Zinellu A; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Pau MC; Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy., Piras B; Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy., Fois AG; Clinical and Interventional Pulmonology, University Hospital Sassari (AOU), 07100 Sassari, Italy.; Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy., Mellino S; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Carru C; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Mangoni AA; Department of Clinical Pharmacology, College of Medicine and Public Health, Flinders Medical Centre, Flinders University, Bedford Park, SA 5042, Australia., Pirina P; Clinical and Interventional Pulmonology, University Hospital Sassari (AOU), 07100 Sassari, Italy.; Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.
المصدر: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Oct 30; Vol. 10 (11). Date of Electronic Publication: 2021 Oct 30.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101668981 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3921 (Print) Linking ISSN: 20763921 NLM ISO Abbreviation: Antioxidants (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2012]-
مستخلص: Chronic obstructive pulmonary disease (COPD) is a progressive disease that is characterized by a state of persistent inflammation and oxidative stress. The presence of oxidative stress in COPD is the result of an imbalance between pro-oxidant and antioxidant mechanisms. The aim of this review was to investigate a possible association between glutathione peroxidase (GPx), a key component of antioxidant defense mechanisms, and COPD. A systematic search for relevant studies was conducted in the electronic databases PubMed, Web of Science, Scopus, and Google Scholar, from inception to June 2021. Standardized mean differences (SMDs) were used to express the differences in GPx concentrations between COPD patients and non-COPD subjects. Twenty-four studies were identified. In 15 studies assessing whole blood/erythrocytes (GPx isoform 1), the pooled results showed that GPx concentrations were significantly lower in patients with COPD (SMD = -1.91, 95% CI -2.55 to -1.28, p < 0.001; moderate certainty of evidence). By contrast, in 10 studies assessing serum/plasma (GPx isoform 3), the pooled results showed that GPx concentrations were not significantly different between the two groups (very low certainty of evidence). The concentration of GPx-1, but not GPx-3, is significantly lower in COPD patients, suggesting an impairment of antioxidant defense mechanisms in this group.
References: Stat Med. 2002 Jun 15;21(11):1539-58. (PMID: 12111919)
Am J Respir Cell Mol Biol. 2020 May;62(5):598-607. (PMID: 31801023)
Clin Biochem. 2007 Sep;40(13-14):958-63. (PMID: 17631288)
J Med Biochem. 2017 Oct 28;36(4):331-340. (PMID: 30581330)
Cell Biochem Funct. 2010 Aug;28(6):448-53. (PMID: 20648694)
Antioxid Redox Signal. 2011 Oct 1;15(7):1957-97. (PMID: 21087145)
Biochem Cell Biol. 2015 Dec;93(6):574-80. (PMID: 26369587)
Antioxid Redox Signal. 2020 Sep 1;33(7):498-516. (PMID: 31822117)
J Clin Epidemiol. 2001 Oct;54(10):1046-55. (PMID: 11576817)
Adv Exp Med Biol. 2021;1304:187-204. (PMID: 34019270)
Biomarkers. 2004 Nov-Dec;9(6):461-9. (PMID: 15849066)
J Appl Physiol (1985). 2015 Aug 15;119(4):363-73. (PMID: 26089546)
Oxid Med Cell Longev. 2013;2013:897075. (PMID: 24089631)
Respir Care. 2015 Dec;60(12):1729-42. (PMID: 26106205)
Biochim Biophys Acta. 2009 Nov;1790(11):1486-500. (PMID: 19376195)
BMJ. 2021 Mar 29;372:n71. (PMID: 33782057)
Biometrics. 1994 Dec;50(4):1088-101. (PMID: 7786990)
Chest. 2013 Jul;144(1):266-273. (PMID: 23880677)
Nat Rev Dis Primers. 2015 Dec 03;1:15076. (PMID: 27189863)
Can Respir J. 2013 Jan-Feb;20(1):35-41. (PMID: 23457673)
BMC Med Res Methodol. 2011 Apr 07;11:41. (PMID: 21473747)
Treat Respir Med. 2005;4(3):175-200. (PMID: 15987234)
BMC Med Res Methodol. 2014 Dec 19;14:135. (PMID: 25524443)
Biometrics. 2000 Jun;56(2):455-63. (PMID: 10877304)
Int J Chron Obstruct Pulmon Dis. 2018 May 24;13:1691-1700. (PMID: 29872287)
Int J Tuberc Lung Dis. 2013 Aug;17(8):1104-9. (PMID: 23827037)
Wien Klin Wochenschr. 2007;119(13-14):428-34. (PMID: 17671825)
BMC Med Res Methodol. 2005 Apr 20;5:13. (PMID: 15840177)
Biochim Biophys Acta. 2013 May;1830(5):3289-303. (PMID: 23201771)
Respirology. 2013 Oct;18(7):1069-75. (PMID: 23683270)
Biol Trace Elem Res. 2014 Oct;161(1):20-31. (PMID: 25074430)
Redox Biol. 2020 Jun;33:101544. (PMID: 32336666)
Oxid Med Cell Longev. 2020 May 14;2020:4982324. (PMID: 32509143)
Sci Rep. 2020 Jul 14;10(1):11587. (PMID: 32665564)
Antioxidants (Basel). 2020 Nov 18;9(11):. (PMID: 33218130)
Inhal Toxicol. 2010 Aug;22(10):868-74. (PMID: 20583895)
Respir Care. 2012 Dec;57(12):2090-4. (PMID: 22710284)
Eur Respir J. 2019 Jul 18;54(1):. (PMID: 31000678)
Indian J Physiol Pharmacol. 2012 Oct-Dec;56(4):345-52. (PMID: 23781654)
Int J Mol Sci. 2020 Sep 30;21(19):. (PMID: 33007849)
Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. (PMID: 28128970)
J Clin Med. 2017 Feb 15;6(2):. (PMID: 28212273)
Inflammation. 2005 Feb;29(1):23-32. (PMID: 16502343)
Front Biosci (Schol Ed). 2013 Jan 01;5:638-49. (PMID: 23277075)
Exp Lung Res. 2011 May;37(4):195-204. (PMID: 21309732)
Glob Health Epidemiol Genom. 2018 Apr 6;3:e4. (PMID: 29868229)
معلومات مُعتمدة: RASSR82005 Sardinian Fondo di Sviluppo e Coesione (FSC) 2014 - 2020, Patto per lo Sviluppo della Regione Sardegna, L.R.7-2017; annualità 2020 Fondo di Ateneo per la Ricerca
فهرسة مساهمة: Keywords: antioxidant defense systems; chronic obstructive pulmonary disease; glutathione peroxidase; oxidative stress
تواريخ الأحداث: Date Created: 20211127 Latest Revision: 20211130
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8615188
DOI: 10.3390/antiox10111745
PMID: 34829616
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-3921
DOI:10.3390/antiox10111745