دورية أكاديمية
Influence of diabetes mellitus interactions with cardiovascular risk factors on post-myocardial infarction heart failure hospitalizations.
| العنوان: | Influence of diabetes mellitus interactions with cardiovascular risk factors on post-myocardial infarction heart failure hospitalizations. |
|---|---|
| المؤلفون: | Yandrapalli S; Division of Cardiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. Electronic address: syandrapalli@mgh.harvard.edu., Malik AH; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Namrata F; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Pemmasani G; Department of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA., Bandyopadhyay D; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Vallabhajosyula S; Section of Cardiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Aronow WS; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Frishman WH; Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Jain D; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Cooper HA; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA., Panza JA; Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA. |
| المصدر: | International journal of cardiology [Int J Cardiol] 2022 Feb 01; Vol. 348, pp. 140-146. Date of Electronic Publication: 2021 Dec 02. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
| مواضيع طبية MeSH: | Cardiovascular Diseases* , Diabetes Mellitus*/diagnosis , Diabetes Mellitus*/epidemiology , Heart Failure*/diagnosis , Heart Failure*/epidemiology , Myocardial Infarction*/diagnosis , Myocardial Infarction*/epidemiology, Adult ; Heart Disease Risk Factors ; Hospitalization ; Humans ; Retrospective Studies ; Risk Factors |
| مستخلص: | Objective: There is a paucity of information regarding how cardiovascular risk factors (RF) modulate the impact of diabetes mellitus (DM) on the heart failure hospitalization (HFH) risk following an acute myocardial infarction (AMI). Methods: Adult survivors of an AMI were retrospectively identified from the 2014 US Nationwide Readmissions Database. The impact of DM on the risk for a 6-month HFH was studied in subgroups of RFs using multivariable logistic regression to adjust for baseline risk differences. Individual interactions of DM with RFs were tested. Results: Of 237,549 AMI survivors, 37.2% patients had DM. Primary outcome occurred in 12,934 patients (5.4%), at a 106% higher rate in DM patients (7.9% vs 4.0%, p < 0.001), which was attenuated to a 45% higher adjusted risk. Higher HFH risk in DM patients was consistent across subgroups and significant interactions were present between DM and other RFs. The increased HFH risk with DM was more pronounced in patients without certain HF RFs compared with those with these RFs [age < 65: OR for DM 1.84 (1.58-2.13) vs age ≥ 65: OR 1.34 (1.24-1.45); HF absent during index AMI: OR for DM 1.87 (1.66-2.10) vs HF present: OR 1.24 (1.14-1.34); atrial fibrillation absent: OR for DM 1.57 (1.46-1.68) vs present: OR 1.19 (1.06-1.33); P Conclusions: AMI survivors with DM had a higher risk of 6-month HFHs. The impact of DM on the increased HFH risk was more pronounced in patients without certain RFs suggesting that more aggressive preventive strategies related to DM and HF are needed in these subgroups to prevent or delay the onset of HFHs. (Copyright © 2021. Published by Elsevier B.V.) |
| التعليقات: | Comment in: Int J Cardiol. 2022 Jul 15;359:118-119. (PMID: 35439587) |
| فهرسة مساهمة: | Keywords: Acute myocardial infarction; Diabetes mellitus; Heart failure; Outcomes; Risk factors |
| تواريخ الأحداث: | Date Created: 20211205 Date Completed: 20220126 Latest Revision: 20220914 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ijcard.2021.11.086 |
| PMID: | 34864085 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1874-1754 |
|---|---|
| DOI: | 10.1016/j.ijcard.2021.11.086 |