دورية أكاديمية
أعرض في EDS

Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world's most diverse rainfores.

التفاصيل البيبلوغرافية
العنوان: Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world's most diverse rainfores.
المؤلفون: Borges A; Center for the Development of Scientific Research (CEDIC), Asunción, Paraguay.; Laboratory of Molecular Biology of Toxins and Receptors, Institute of Experimental Medicine, School of Medicine, Central University of Venezuela, Caracas, Venezuela., Graham MR; Department of Biology, Eastern Connecticut State University, Willimantic, CT, United States., Cândido DM; Laboratory of Arthropods, Butantan Institute, São Paulo, SP, Brazil., Pardal PPO; Laboratory of Medical Entomology and Venomous Animals, Center of Tropical Medicine, Federal University of Pará (UFPA), Belém, PA, Brazil.
المصدر: The journal of venomous animals and toxins including tropical diseases [J Venom Anim Toxins Incl Trop Dis] 2021 Nov 29; Vol. 27, pp. e20210028. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: CEVAP Country of Publication: Brazil NLM ID: 101201501 Publication Model: eCollection Cited Medium: Print ISSN: 1678-9199 (Print) Linking ISSN: 16789180 NLM ISO Abbreviation: J Venom Anim Toxins Incl Trop Dis Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2019- : Botucatu, SP, Brazil : CEVAP
Original Publication: Botucatu, SP, Brazil : CEVAP, c2003-
مستخلص: Venom from Amazonian scorpions of the genus Tityus contains components capable of eliciting a distinct clinical, mostly neurological, syndrome. This contrasts with the mainly autonomic manifestations produced after envenomation by congeneric southern and northern South American species. Herein, we summarize Pan-Amazonian scorpionism by synthesizing available toxinological, clinical, and molecular data gathered from all affected areas in Amazonia, including Brazil, Ecuador, Colombia, Peru, Venezuela, and French Guiana. We searched multiple databases, as well as our own records, for reports of scorpion envenomations in Amazonia by confirmed Tityus spp., and compared the clinical manifestations. To help uncover clinical and venom relationships among problematic species, we explored phylogenetic relationships with a rate-calibrated analysis of mitochondrial COI data from available species. The possible existence of diversity gradients for venom toxic and immunogenic components despite the predicted strong phylogenetic association among species is underscored by discussed clinical and toxinological findings. A multicentric effort, involving all nations affected by this neglected disease, is urgently needed to offer alternatives for treating and understanding this pathology, including the preparation of neutralizing antibodies with a broad range of efficacy.
Competing Interests: Competing interests: The authors declare that they have no competing interests.
References: J Venom Anim Toxins Incl Trop Dis. 2020 Sep 11;26:e202000038. (PMID: 32973890)
Toxicon. 2020 Nov;187:245-254. (PMID: 32991937)
Neurosci Lett. 2019 Jan 1;688:41-48. (PMID: 29421541)
Mol Immunol. 2020 Mar;119:144-153. (PMID: 32023500)
Toxicon. 2015 Oct;105:56-61. (PMID: 26344916)
Trans R Soc Trop Med Hyg. 2011 Jul;105(7):364-9. (PMID: 21601228)
Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):404-8. (PMID: 18926933)
Comp Biochem Physiol C Toxicol Pharmacol. 2005 May;141(1):85-92. (PMID: 15996531)
Peptides. 2014 Jan;51:35-45. (PMID: 24184590)
Mol Pharmacol. 2006 Jul;70(1):340-7. (PMID: 16638971)
Mol Biol Evol. 2018 Jun 1;35(6):1547-1549. (PMID: 29722887)
Toxicon. 2019 Nov;169:68-80. (PMID: 31494205)
Toxicon. 2000 Aug;38(8):1005-7. (PMID: 10836905)
Life Sci. 2000;66(3):185-92. (PMID: 10665992)
Toxicon. 2020 Dec;188:65-75. (PMID: 33065199)
Toxicon. 2005 Dec 15;46(8):831-44. (PMID: 16274721)
Vaccine. 2010 Feb 3;28(5):1168-76. (PMID: 19948263)
Toxins (Basel). 2012 Nov 01;4(11):1082-119. (PMID: 23202307)
Med Trop (Mars). 2008 Jun;68(3):215-21. (PMID: 18689308)
Toxicon. 1974 Mar;12(2):209-11. (PMID: 4851415)
J Med Chem. 2020 Sep 10;63(17):9500-9511. (PMID: 32787139)
Toxicon. 2005 Aug;46(2):210-7. (PMID: 15970301)
Toxicon. 2010 Feb-Mar;55(2-3):436-54. (PMID: 19799925)
Wilderness Environ Med. 2010 Dec;21(4):282-90. (PMID: 21168779)
Biomedica. 2010 Jan-Mar;30(1):126-39. (PMID: 20890557)
Toxicon. 2002 May;40(5):557-62. (PMID: 11821128)
Toxicon. 2013 Oct;73:56-62. (PMID: 23791738)
Toxicon. 2006 Mar 15;47(4):437-44. (PMID: 16466762)
J Venom Anim Toxins Incl Trop Dis. 2016 Aug 26;22(1):24. (PMID: 27570532)
Cerebellum. 2003;2(1):2-9. (PMID: 12882229)
Toxicon. 2016 Sep 1;119:266-9. (PMID: 27368713)
PLoS Negl Trop Dis. 2015 May 21;9(5):e0003701. (PMID: 25996940)
Gac Med Mex. 1996 Nov-Dec;132(6):645-8. (PMID: 9019428)
Toxicon. 2004 May;43(6):737-40. (PMID: 15109895)
Mol Phylogenet Evol. 2017 May;110:39-49. (PMID: 28259729)
Rev Soc Bras Med Trop. 2003 May-Jun;36(3):349-53. (PMID: 12908035)
Rev Soc Bras Med Trop. 2017 May-Jun;50(3):427-430. (PMID: 28700068)
PLoS One. 2015 Jun 10;10(6):e0128819. (PMID: 26061734)
Mol Biol Evol. 2012 Aug;29(8):1969-73. (PMID: 22367748)
Chest. 1990 Jan;97(1):118-20. (PMID: 2295229)
PLoS One. 2008 Jul 23;3(7):e2738. (PMID: 18648512)
Toxicon. 1999 Jan;37(1):159-65. (PMID: 9920487)
PLoS One. 2018 Mar 21;13(3):e0193739. (PMID: 29561852)
Toxicon. 2020 Apr 30;178:8-12. (PMID: 32094100)
Med Sci Monit. 2005 Apr;11(4):CR196-202. (PMID: 15795701)
Zookeys. 2018 Jun 5;(764):27-90. (PMID: 29899674)
Toxicon. 2002 Sep;40(9):1339-46. (PMID: 12220720)
Toxicol Sci. 2014 Dec;142(2):418-26. (PMID: 25239630)
Mol Phylogenet Evol. 2016 Jan;94(Pt A):159-70. (PMID: 26321226)
Brain Res. 2000 Dec 15;886(1-2):5-14. (PMID: 11119683)
Toxicon. 2014 Oct;89:17-25. (PMID: 25011046)
Protein Sci. 2002 Feb;11(2):390-400. (PMID: 11790849)
J Emerg Med. 2019 Oct;57(4):554-559. (PMID: 31564443)
Toxicon. 1994 Aug;32(8):989-98. (PMID: 7985203)
Toxicon. 2019 Sep;167:134-143. (PMID: 31207348)
Intensive Care Med. 2015 Oct;41(10):1871-2. (PMID: 26208749)
Mediators Inflamm. 2010;2010:903295. (PMID: 20300540)
Eur J Neurosci. 2000 Aug;12(8):2823-32. (PMID: 10971624)
Biochim Biophys Acta. 2002 Dec 16;1601(2):123-31. (PMID: 12445473)
Toxicon. 1997 May;35(5):759-71. (PMID: 9203301)
J Venom Anim Toxins Incl Trop Dis. 2014 Feb 11;20(1):3. (PMID: 24517181)
Peptides. 2017 Sep;95:106-115. (PMID: 28735770)
Intensive Care Med. 2020 Mar;46(3):401-410. (PMID: 32125457)
BMJ. 2021 Mar 29;372:n160. (PMID: 33781993)
Toxicon. 2017 Feb;126:51-58. (PMID: 28012802)
Toxicon. 2003 Jun;41(8):971-7. (PMID: 12875871)
PLoS One. 2012;7(2):e30478. (PMID: 22355312)
Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):142-150. (PMID: 30463697)
Acta Trop. 2020 Apr;204:105346. (PMID: 31982434)
BMC Genomics. 2010 Jul 28;11:452. (PMID: 20663230)
Evolution. 2002 Jul;56(7):1489-97. (PMID: 12206248)
FEBS Lett. 2000 Dec 8;486(2):117-20. (PMID: 11113450)
Toxicon. 2007 Dec 1;50(7):1005-10. (PMID: 17868753)
Toxicon. 2018 Mar 1;143:51-58. (PMID: 29337221)
Am J Trop Med Hyg. 1995 Mar;52(3):277-80. (PMID: 7694971)
J Proteomics. 2018 Jan 6;170:70-79. (PMID: 28918200)
J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 15;803(1):55-66. (PMID: 15025998)
Toxicon. 2012 Sep 15;60(4):603-6. (PMID: 22683677)
Nucleic Acids Res. 2004 Mar 19;32(5):1792-7. (PMID: 15034147)
Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6023-6034. (PMID: 32132200)
Acta Trop. 2018 Feb;178:1-9. (PMID: 29079184)
Biomed Pharmacother. 2019 Oct;118:109152. (PMID: 31376652)
Toxicon. 2015 Mar;96:68-73. (PMID: 25549940)
فهرسة مساهمة: Keywords: Amazonia; Scorpion antivenom; Scorpionism; Tityus
تواريخ الأحداث: Date Created: 20211210 Latest Revision: 20240210
رمز التحديث: 20240210
مُعرف محوري في PubMed: PMC8629433
DOI: 10.1590/1678-9199-JVATITD-2021-0028
PMID: 34887908
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-9199
DOI:10.1590/1678-9199-JVATITD-2021-0028