دورية أكاديمية
أعرض في EDS

Fungal keratitis due to Scopulariopsis brevicaulis and a potential promising therapeutic effect of antibacterial agents: A case report.

التفاصيل البيبلوغرافية
العنوان: Fungal keratitis due to Scopulariopsis brevicaulis and a potential promising therapeutic effect of antibacterial agents: A case report.
المؤلفون: Kaplan NM; Department of Pathology and Microbiology, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan., Al-Dwairi RA; Department of Special Surgery (Ophthalmology), King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan., AlRabadi NN; Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
المصدر: Medicine [Medicine (Baltimore)] 2021 Dec 10; Vol. 100 (49), pp. e28203.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Contact Lenses, Hydrophilic*, Anti-Bacterial Agents/*therapeutic use , Corneal Ulcer/*microbiology , Eye Infections, Fungal/*complications , Eye Infections, Fungal/*diagnosis , Keratitis/*drug therapy , Scopulariopsis/*isolation & purification, Adolescent ; Antifungal Agents/therapeutic use ; Corneal Ulcer/diagnosis ; Corneal Ulcer/drug therapy ; Eye Infections, Fungal/drug therapy ; Female ; Humans ; Keratitis/diagnosis
مستخلص: Introduction: Microbial keratitis is a serious potentially blinding corneal infection. Contact lens wear remains the most common predisposing factor. Fungal keratitis represent only a small fraction of the overall number of cases of contact lens-associated microbial keratitis, however they are proportionally more severe.
Patient Concerns: An 18-year-old female, who occasionally used eye cosmetic soft contact lenses, presented with pain, redness, and blurring of vision in her left eye.
Diagnosis: The left eye showed decreased visual acuity, central corneal ulcer and abscess, and severe ciliary injection. A provisional diagnosis of infectious keratitis was considered.
Intervention: Corneal scrapings were aseptically collected and directly inoculated onto sterile bacterial and fungal agar plates that were immediately incubated. The patient was admitted and started on topical and systemic antibacterial agents.
Outcomes: The infection showed signs of satisfactory clinical resolution. However, the mold Scopulariopsis brevicaulis was isolated in pure colonies 5 days after presentation.
Conclusion: We report the first case from Jordan of fungal keratitis caused by the mold S brevicaulis. A high index of suspicion is required for fungal keratitis caused by S brevicaulis in immunocompetent patients who wear contact lenses despite its rarity. This fungal infection was successfully treated using antibacterial agents. However, larger studies are recommended to investigate the clinical effectiveness of antimicrobial agents that have both antibacterial and antifungal effects and to assess their role as empirical therapeutic modalities for infectious keratitis.
Competing Interests: The authors have no funding and conflicts of interest to disclose.
(Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
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المشرفين على المادة: 0 (Anti-Bacterial Agents)
0 (Antifungal Agents)
تواريخ الأحداث: Date Created: 20211210 Date Completed: 20220207 Latest Revision: 20230927
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8663826
DOI: 10.1097/MD.0000000000028203
PMID: 34889303
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000028203