تقرير
Recognition and management of vitamin B12 deficiency: Report of four cases with oral manifestations.
العنوان: | Recognition and management of vitamin B12 deficiency: Report of four cases with oral manifestations. |
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المؤلفون: | da Silva WR; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Dos Santos AA; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Xerez MC; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., de Morais EF; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., de Oliveira PT; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., da Silveira ÉJD; Dentistry Sciences Posto Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. |
المصدر: | Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [Spec Care Dentist] 2022 Jul; Vol. 42 (4), pp. 410-415. Date of Electronic Publication: 2021 Dec 13. |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: American Dental Association Country of Publication: United States NLM ID: 8103755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-4505 (Electronic) Linking ISSN: 02751879 NLM ISO Abbreviation: Spec Care Dentist |
أسماء مطبوعة: | Original Publication: [Chicago : American Dental Association, c1981- |
مواضيع طبية MeSH: | Glossitis*/complications , Glossitis*/drug therapy , Tongue Diseases* , Vitamin B 12 Deficiency*/complications , Vitamin B 12 Deficiency*/diagnosis , Vitamin B 12 Deficiency*/drug therapy, Humans ; Vitamin B 12/therapeutic use |
مستخلص: | Vitamins are organic compounds present in low concentrations in food, performing vital and specific cell metabolism functions. Vitamin B12 is essential for red blood cell formation in the bone marrow and its deficiency is caused, mainly, by gastrointestinal malabsorption. In addition to systemic manifestations, oral signs and symptoms have also been associated to this condition such as glossitis, papillary atrophy, painful erythema areas, burning sensation, dysgeusia, lingual paresthesia and itching. This study aims to report four cases of oral manifestations caused by vitamin B12 deficiency. All patients presented oral mucosa lesions. Vitamin B12 deficiency was diagnosed based in clinical characteristics and complementary exams. Oral supplementation for vitamin B12 deficiency was conducted/realized in three patients, while one patient was treated with parenteral doses. All of them showed partial or total remission of the signs and symptoms. (© 2021 Special Care Dentistry Association and Wiley Periodicals LLC.) |
References: | Kim J, Kim MJ, Kho HS. Oral manifestations in vitamin B12 deficiency patients with or without history of gastrectomy. BMC Oral Health. 2016;16(1):60. Langan RC, Goodbred AJ. Vitamin B12 deficiency: recognition and management. Am Fam Physician. 2017;96(6):384-389. Pontes HAR, Neto NC, Ferreira KB, et al. Oral manifestations of vitamin B12 deficiency: a case report. J Can Dent Assoc. 2009;75(7):533-537. Brescoll J, Daveluy S. A review of vitamin B12 in dermatology. Am J Clin Dermatol. 2015;16(1):27-33. Chang JY, Wang YP, Wu YC, Cheng SJ, Chen HM, Sun A. Blood profile of oral mucosal disease patients with both vitamin B12 and iron deficiencies. J Formos Med Assoc. 2015;114(6):532-538. Dali-Youcef N, Andrès E. An update on cobalamin deficiency in adults. QJM. 2009;102(1):17-28. Green R, Allen LH, Bjørke-Monsen AL, et al. Vitamin B12 deficiency. Nat Rev Dis Primers. 2017;3:17040. Andrès E, Nachit M, Guillet-Thibault J. Oral manifestations of vitamin B12 and B9 deficiencies: a prospective study. J Oral Pathol Med. 2016;45(2):154. Graells J, Ojeda RM, Muniesa C, Gonzalez J, Saavedra J. Glossitis with linear lesions: an early sign of vitamin B12 deficiency. J Am Acad Dermatol. 2009;60(3):498-500. Sun A, Chang JY, Wang YP, Cheng SJ, Chen HM, Chiang CP. Do all the patients with vitamin B12 deficiency have pernicious anemia? J Oral Pathol Med. 2016;45(1):23-27. McNamara KK, Kalmar JR. Erythematous and vascular oral mucosal lesions: a clinicopathologic review of red entities. Head Neck Pathol. 2019;13(1), 4-15. Warnakulasuriya S. White, red, and mixed lesions of oral mucosa: a clinicopathologic approach to diagnosis. Periodontology 2000. 2019;80(1):89-104. Schlosser BJ, Pirigyi M, Mirowski GW. Oral manifestations of hematologic and nutritional diseases. Otolaryngol Clin North Am. 2011;44(1):183-203. Bensky, MJ, Ayalon-Dangur, I, Ayalon-Dangur, R, et al. Comparison of sublingual versus intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency. Drug Delivery Translational Res. 2019;9(3):625-630. Romain, M, Sviri, S, Linton, D M, Stav, I, van HPV. The role of vitamin B12 in the critically ill-a review. Anesthesia Intensive Care. 2016;44(4):447-452. |
فهرسة مساهمة: | Keywords: glossistis; oral manifestations; vitamin B12 deficiency |
المشرفين على المادة: | P6YC3EG204 (Vitamin B 12) |
تواريخ الأحداث: | Date Created: 20211213 Date Completed: 20220721 Latest Revision: 20220721 |
رمز التحديث: | 20231215 |
DOI: | 10.1111/scd.12685 |
PMID: | 34902172 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1754-4505 |
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DOI: | 10.1111/scd.12685 |