دورية أكاديمية
Stand-Alone Use of Artificial Intelligence for Digital Mammography and Digital Breast Tomosynthesis Screening: A Retrospective Evaluation.
| العنوان: | Stand-Alone Use of Artificial Intelligence for Digital Mammography and Digital Breast Tomosynthesis Screening: A Retrospective Evaluation. |
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| المؤلفون: | Romero-Martín S; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.)., Elías-Cabot E; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.)., Raya-Povedano JL; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.)., Gubern-Mérida A; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.)., Rodríguez-Ruiz A; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.)., Álvarez-Benito M; From the Breast Cancer Unit, Department of Radiology, Hospital Universitario Reina Sofía, Av Menéndez Pidal s/n, Córdoba 14004, Spain (S.R., E.E., J.L.R., M.Á.); Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain (S.R., E.E., J.L.R., M.Á.); and Department of Clinical Science, ScreenPoint Medical, Nijmegen, the Netherlands (A.G., A.R.). |
| المصدر: | Radiology [Radiology] 2022 Mar; Vol. 302 (3), pp. 535-542. Date of Electronic Publication: 2021 Dec 14. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Radiological Society of North America Country of Publication: United States NLM ID: 0401260 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-1315 (Electronic) Linking ISSN: 00338419 NLM ISO Abbreviation: Radiology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Easton, PA : Radiological Society of North America Original Publication: [Illinois?] : Radiological Society of North America, [1923]- |
| مواضيع طبية MeSH: | Artificial Intelligence*, Breast Neoplasms/*diagnostic imaging , Mammography/*methods , Radiographic Image Interpretation, Computer-Assisted/*methods, Early Detection of Cancer ; Female ; Humans ; Middle Aged ; Retrospective Studies ; Sensitivity and Specificity |
| مستخلص: | Background Use of artificial intelligence (AI) as a stand-alone reader for digital mammography (DM) or digital breast tomosynthesis (DBT) breast screening could ease radiologists' workload while maintaining quality. Purpose To retrospectively evaluate the stand-alone performance of an AI system as an independent reader of DM and DBT screening examinations. Materials and Methods Consecutive screening-paired and independently read DM and DBT images acquired between January 2015 and December 2016 were retrospectively collected from the Tomosynthesis Cordoba Screening Trial. An AI system computed a cancer risk score (range, 1-100) for DM and DBT examinations independently. AI stand-alone performance was measured using the area under the receiver operating characteristic curve (AUC) and sensitivity and recall rate at different operating points selected to have noninferior sensitivity compared with the human readings (noninferiority margin, 5%). The recall rate of AI and the human readings were compared using a McNemar test. Results A total of 15 999 DM and DBT examinations (113 breast cancers, including 98 screen-detected and 15 interval cancers) from 15 998 women (mean age, 58 years ± 6 [standard deviation]) were evaluated. AI achieved an AUC of 0.93 (95% CI: 0.89, 0.96) for DM and 0.94 (95% CI: 0.91, 0.97) for DBT. For DM, AI achieved noninferior sensitivity as a single (58.4%; 66 of 113; 95% CI: 49.2, 67.1) or double (67.3%; 76 of 113; 95% CI: 58.2, 75.2) reader, with a reduction in recall rate ( P < .001) of up to 2% (95% CI: -2.4, -1.6). For DBT, AI achieved noninferior sensitivity as a single (77%; 87 of 113; 95% CI: 68.4, 83.8) or double (81.4%; 92 of 113; 95% CI: 73.3, 87.5) reader, but with a higher recall rate ( P < .001) of up to 12.3% (95% CI: 11.7, 12.9). Conclusion Artificial intelligence could replace radiologists' readings in breast screening, achieving a noninferior sensitivity, with a lower recall rate for digital mammography but a higher recall rate for digital breast tomosynthesis. Published under a CC BY 4.0 license. See also the editorial by Fuchsjäger and Adelsmayr in this issue. |
| التعليقات: | Comment in: Radiology. 2021 Dec 14;:212675. (PMID: 34904877) |
| تواريخ الأحداث: | Date Created: 20211214 Date Completed: 20220304 Latest Revision: 20220304 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1148/radiol.211590 |
| PMID: | 34904872 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1527-1315 |
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| DOI: | 10.1148/radiol.211590 |