دورية أكاديمية
أعرض في EDS

Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis.

التفاصيل البيبلوغرافية
العنوان: Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis.
المؤلفون: Abu-Zaid MH; Rheumatology and Rehabilitation, Tanta University, Tanta, Egypt., Salah S; Pediatric Rheumatology, Cairo University, Cairo, Egypt., Lotfy HM; Pediatric Rheumatology, Cairo University, Cairo, Egypt., El Gaafary M; Community Medicine and Public Health, Ain Shams University, Cairo, Egypt., Abdulhady H; Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt., Tabra SAA; Rheumatology and Rehabilitation, Tanta University, Tanta, Egypt., Salah H; Pediatric Rheumatology, Cairo University, Cairo, Egypt., Farag Y; Pediatric Rheumatology, Cairo University, Cairo, Egypt., Eissa M; Rheumatology, Cairo University, Cairo, Egypt., Maher SE; Pediatric Rheumatology, Minia University, Minia, Egypt., Radwan A; Rheumatology and Rehabilitation, Sohag University, Sohag, Egypt., El-Shanawany AT; Rheumatology and Rehabilitation, Menoufia University, Shibin El Kom, Egypt., Medhat BM; Rheumatology and Rehabilitation, Cairo University, Cairo, Egypt., El Mikkawy D; Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt., Mosad Mosa D; Rheumatology, Mansoura University, Mansoura, Egypt., El Deriny G; Pediatrics, Alexandria University, Alexandria, Egypt., Mortada M; Rheumatology and Rehabilitation, Zagazig University, Zagazig, Egypt., Osman NS; Pediatrics, Assiut University, Assiut, Egypt., Fouad NA; Rheumatology and Rehabilitation, Fayoum University, Fayoum, Egypt., Elkaraly NE; Rheumatology and Rehabilitation, Suez Canal University, Ismailia, Egypt., Mohamed SS; Rheumatology and Rehabilitation, Cairo University, Cairo, Egypt., Hassan WA; Rheumatology and Rehabilitation, Benha University, Benha, Egypt., Amer YA; Rheumatology and Rehabilitation, Zagazig University, Zagazig, Egypt., Nasef SI; Rheumatology and Rehabilitation, Suez Canal University, Ismailia, Egypt., El Miedany Y; Professor, Canterbury Christ Church University, Canterbury, England.
المصدر: Therapeutic advances in musculoskeletal disease [Ther Adv Musculoskelet Dis] 2021 Dec 09; Vol. 13, pp. 1759720X211059610. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Sage Country of Publication: England NLM ID: 101517322 Publication Model: eCollection Cited Medium: Print ISSN: 1759-720X (Print) Linking ISSN: 1759720X NLM ISO Abbreviation: Ther Adv Musculoskelet Dis Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: - : London : Sage
Original Publication: Oct. 2009- : Thousand Oaks, CA : Sage Publications
مستخلص: IgA vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the most common cause of systemic vasculitis in childhood. Given its potential life-threatening systemic complications, early and accurate diagnosis as well as management of IgAV represent a major challenge for health care professionals. This study was carried out to attain an evidence-based expert consensus on a treat-to-target management approach for IgAV using Delphi technique. The preliminary scientific committee identified a total of 16 key clinical questions according to the patient, intervention, comparison, and outcomes (PICO) approach. An evidence-based, systematic, literature review was conducted to compile evidence for the IgAV management. The core leadership team identified researchers and clinicians with expertise in IgAV management in Egypt upon which experts were gathered from different governorates and health centers across Egypt. Delphi process was implemented (two rounds) to reach a consensus. An online questionnaire was sent to expert panel ( n = 26) who participated in the two rounds. After completing round 2, a total of 20 recommendation items, categorized into two sections were obtained. Agreement with the recommendations (rank 7-9) ranged from 91.7-100%. Consensus was reached (i.e. ⩾75% of respondents strongly agreed or agreed) on the wording of all the 20 clinical standards identified by the scientific committee. Algorithms for the diagnosis and management have been suggested. This was an expert, consensus recommendations for the diagnosis and treatment of IgAV and IgA vasculitic nephritis, based on best available evidence and expert opinion. The guideline presented a strategy of care with a pathway to achieve a state of remission as early as possible.
Plain Language Summary: Given its potential life-threatening systemic complications, early and accurate diagnosis of immunoglobulin A vasculitis represents a major challenge for health care professionals. This work provided cornerstone principles for the management of the condition. Adopting PICO approach and implementing Delphi process a consensus was reached on evidence-based treat-to-target treatment recommendations. This will endorse enhancement and consistency of care of this cohort of patients in standard practice.
Competing Interests: Conflict of interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s), 2021.)
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فهرسة مساهمة: Keywords: Egypt; Egyptian guidelines IgA vasculitis; Henoch-Schönlein purpura; IgA vasculitis; guidelines; vasculitis algorithm
تواريخ الأحداث: Date Created: 20211217 Latest Revision: 20220429
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8669874
DOI: 10.1177/1759720X211059610
PMID: 34917176
قاعدة البيانات: MEDLINE
الوصف
تدمد:1759-720X
DOI:10.1177/1759720X211059610