دورية أكاديمية
أعرض في EDS

Factors Associated with Cancer-Related Pain Requiring High-Dose Opioid Use in Palliative Cancer Patients.

التفاصيل البيبلوغرافية
العنوان: Factors Associated with Cancer-Related Pain Requiring High-Dose Opioid Use in Palliative Cancer Patients.
المؤلفون: Sumimoto H; Department of Medical Oncology, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Hayashi K; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Kimura Y; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Nishikawa A; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Hattori S; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Hasegawa C; Department of Pharmacy, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Morii H; Department of Pharmacy, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Teramoto K; Department of Medical Oncology, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Morita S; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan., Daigo Y; Department of Medical Oncology, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Cancer Center, Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.; Palliative Care Center, and Shiga University of Medical Science Hospital, Otsu, Shiga, Japan.
المصدر: Palliative medicine reports [Palliat Med Rep] 2021 Sep 15; Vol. 2 (1), pp. 237-241. Date of Electronic Publication: 2021 Sep 15 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101770666 Publication Model: eCollection Cited Medium: Internet ISSN: 2689-2820 (Electronic) Linking ISSN: 26892820 NLM ISO Abbreviation: Palliat Med Rep Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: New Rochelle, NY : Mary Ann Liebert, Inc., [2020]-
مستخلص: Background: There are no universal tools to predict the necessity of high-dose opioid use for cancer-related pain. Early recognition and interventions for intractable cancer pain could minimize the distress of palliative patients. Objective: We sought to identify the clinical factors associated with high-dose opioid use in advanced cancer patients to recognize palliative patients who would develop intractable cancer pain, as early as possible. Setting/Subjects: Among 385 in-hospital cancer patients from April 1, 2014 to July 31, 2019, who were referred to the palliative care team for cancer-related pain, clinical factors significantly correlated to high-dose opioid use were retrospectively analyzed. Measurements: We conducted a multiple logistic regression analysis to identify variables significantly related to high-dose opioid use (>120 mg/day oral morphine equivalent dose). Results: Independent factors of high-dose opioid use included younger age (odds ratio [OR] 0.965, 95% confidence interval [CI] 0.944-0.986, p  = 0.001), respiratory cancers (OR 1.882, 95% CI 1.069-3.312, p  < 0.001), and opioid switch (OR 2.869, 95% CI 1.497-5.497, p  = 0.001). The percentage of correct classifications of the regression equation was 86.9%. Conclusions: Younger age, respiratory cancers, and opioid switch were related to high-dose opioid use. Our findings may help palliative caregivers to deal with intractable cancer pain in palliative patients, and thus relieve their distress.
Competing Interests: No competing financial interests exist.
(© Hidetoshi Sumimoto et al., 2021; Published by Mary Ann Liebert, Inc.)
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فهرسة مساهمة: Keywords: cancer-related pain; high-dose opioid; intractable cancer pain
تواريخ الأحداث: Date Created: 20211220 Latest Revision: 20211221
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8675226
DOI: 10.1089/pmr.2021.0037
PMID: 34927147
قاعدة البيانات: MEDLINE
الوصف
تدمد:2689-2820
DOI:10.1089/pmr.2021.0037