دورية أكاديمية
Histological and immunohistochemical features of cutaneous mast cell tumor in six captive four-toed hedgehogs (Atelerix albiventris).
| العنوان: | Histological and immunohistochemical features of cutaneous mast cell tumor in six captive four-toed hedgehogs (Atelerix albiventris). |
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| المؤلفون: | Son NV; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.; Department of Veterinary Pathology, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 10000, Vietnam., Chambers JK; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan., Nakata M; Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, Tokyo 170-0003, Japan.; Vision Vets Group Lab, #201 Naeshiro Bldg., 1-24-6 Komagome, Toshima-ku, Tokyo 170-0003, Japan., Miwa Y; Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, Tokyo 170-0003, Japan.; Vision Vets Group Lab, #201 Naeshiro Bldg., 1-24-6 Komagome, Toshima-ku, Tokyo 170-0003, Japan., Nakayama H; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.; Vision Vets Group Lab, #201 Naeshiro Bldg., 1-24-6 Komagome, Toshima-ku, Tokyo 170-0003, Japan., Uchida K; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. |
| المصدر: | The Journal of veterinary medical science [J Vet Med Sci] 2022 Feb 10; Vol. 84 (2), pp. 208-212. Date of Electronic Publication: 2021 Dec 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japanese Society Of Veterinary Science Country of Publication: Japan NLM ID: 9105360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-7439 (Electronic) Linking ISSN: 09167250 NLM ISO Abbreviation: J Vet Med Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tokyo : Japanese Society Of Veterinary Science |
| مواضيع طبية MeSH: | Hedgehogs* , Mast Cells*, Animals ; Macrophages ; Skin |
| مستخلص: | This report described the histopathological and immunohistochemical features of cutaneous mast cell tumor (MCT) in six hedgehogs. The hedgehogs presented single cutaneous mass with ulcer and crusting. Histologically, the neoplastic lesions were characterized by the proliferation of well-differentiated mast cells (3 cases), and atypical mast cells (3 cases) with one atypical histiocytic morphology. Immunohistochemically, tumor cells were positive for KIT and mast cell tryptase, and were negative for Iba-1. In well-differentiated MCT, all patients were clinically improved and survived more than 365 days after surgical excision, whereas an atypical histiocytic MCT showed aggressive behavior with re-recurrence, and the animal died 115 days after surgery. These findings suggest that, compatible with other animals, well-differentiated MCT has a better prognosis in hedgehogs. |
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| فهرسة مساهمة: | Keywords: cutaneous mast cell tumor; four-toed hedgehog (Atelerix albiventris); histopathology; immunohistochemistry |
| تواريخ الأحداث: | Date Created: 20211223 Date Completed: 20220215 Latest Revision: 20220326 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8920718 |
| DOI: | 10.1292/jvms.21-0560 |
| PMID: | 34937843 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1347-7439 |
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| DOI: | 10.1292/jvms.21-0560 |