دورية أكاديمية
أعرض في EDS

Venous thromboembolism during pregnancy and postpartum period.

التفاصيل البيبلوغرافية
العنوان: Venous thromboembolism during pregnancy and postpartum period.
المؤلفون: Bukhari S; Department of Medicine, Temple University, Philadelphia, PA., Fatima S; Department of Medicine, University of Pittsburgh Medical Center McKeesport Hospital, McKeesport, PA., Barakat AF; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA., Fogerty AE; Division of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Weinberg I; Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Elgendy IY; Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar. Electronic address: iyelgendy@gmail.com.
المصدر: European journal of internal medicine [Eur J Intern Med] 2022 Mar; Vol. 97, pp. 8-17. Date of Electronic Publication: 2021 Dec 20.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : Amsterdam, The Netherlands : Elsevier Science
Original Publication: Basingstoke, Hampshire, UK : Published by the Macmillan Press on behalf of the European Association of Internal Medicine, c1989-
مواضيع طبية MeSH: Pregnancy Complications, Cardiovascular*/epidemiology , Pregnancy Complications, Cardiovascular*/therapy , Venous Thromboembolism*/drug therapy , Venous Thromboembolism*/epidemiology, Female ; Humans ; Postpartum Period ; Pregnancy ; Risk Factors
مستخلص: Venous thromboembolism (VTE) is one of the leading causes of maternal mortality. Rates of VTE during pregnancy and the postpartum period have not decreased over the past two decades and pregnancyassociated VTE continues to pose a significant health challenge. Pregnant and postpartum women are at a higher risk for VTE owing to many factors. There are hormonally mediated and pregnancy-specific alterations of coagulation that favor thrombosis, including increased production of clotting factors. There are physiologic and anatomic mechanisms that also contribute, including a decreased rate of venous blood flow from the lower extemities as pregnancy progresses. Cesarean delivery also introduces VTE risk. In addition, studies have demonstrated that pregnancy-associated complications such as pre-eclampsia or peri-partum infections are associated with increased VTE rates. In this review, we discuss the recent epidemiological studies, pathogenesis, risk factors and clinical presentation as well as therapeutic options for VTE during pregnancy and the postpartum period. We also provide proposed diagnostic algorithms for diagnosis and management of VTE during pregnancy and the postpartum period based on updated evidence. Finally, we highlight knowledge gaps to guide future research.
(Copyright © 2021. Published by Elsevier B.V.)
التعليقات: Comment in: Eur J Intern Med. 2022 Mar;97:32-33. (PMID: 35120747)
فهرسة مساهمة: Keywords: Deep venous thrombosis; Maternal mortality; Postpartum; Pregnancy; Pulmonary embolism; Venous thromboembolism
تواريخ الأحداث: Date Created: 20211224 Date Completed: 20220428 Latest Revision: 20220428
رمز التحديث: 20240628
DOI: 10.1016/j.ejim.2021.12.013
PMID: 34949492
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-0828
DOI:10.1016/j.ejim.2021.12.013