دورية أكاديمية
أعرض في EDS

Linear and non-linear analyses of autonomic modulation in uncontrolled and controlled elderly resistant hypertensives.

التفاصيل البيبلوغرافية
العنوان: Linear and non-linear analyses of autonomic modulation in uncontrolled and controlled elderly resistant hypertensives.
المؤلفون: Rubio TA; Hypertension Clinic, Internal Medicine Department, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil., Rodrigues B; Laboratory of Cardiovascular Investigation & Exercise, School of Physical Education, University of Campinas (UNICAMP), Campinas, SP, Brazil., da Costa LMC; Hypertension Clinic, Internal Medicine Department, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil., Ferreira-Melo SE; Cardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil., Tacito LHB; Surgery and Clinical Divisions, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil., Moreno B; Cardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil., Martin JFV; Hypertension Clinic, Internal Medicine Department, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil., Cestario EDES; Hypertension Clinic, Internal Medicine Department, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil., Godoy MF; Cardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil., Moreno-Junior H; Cardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil., Yugar-Toledo JC; Hypertension Clinic, Internal Medicine Department, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil. Electronic address: yugarjuan@uol.com.br.
المصدر: Experimental gerontology [Exp Gerontol] 2022 Mar; Vol. 159, pp. 111686. Date of Electronic Publication: 2022 Jan 05.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE
أسماء مطبوعة: Publication: Tarrytown Ny : Elsevier Science
Original Publication: Oxford.
مواضيع طبية MeSH: Hypertension* , Pulse Wave Analysis*, Aged ; Autonomic Nervous System ; Blood Pressure/physiology ; Humans
مستخلص: Resistant hypertension (RHT) is associated with worse outcomes among patients, and sympathetic overactivity is a challenge in treating this clinical condition. Here, we evaluated the autonomic modulation (by linear and non-linear analyses), central blood pressure, and pulse wave velocity in controlled and uncontrolled RHT patients, as well as those in use of beta-blockers. We observed that uncontrolled RHT patients display, in addition to an increase in peripheral blood pressure, presented higher central blood pressure values concerning controlled RHT. Furthermore, despite the use of beta-blockers, both patients in the RHT + beta-blockers and uncontrolled RHT groups had negative changes in autonomic balance as compared with controlled RHT. These results reinforce the importance of autonomic nervous system interventions in managing arterial hypertension.
(Copyright © 2021. Published by Elsevier Inc.)
فهرسة مساهمة: Keywords: Arterial stiffness; Central blood pressure; Heart rate variability; Hypertension
تواريخ الأحداث: Date Created: 20220107 Date Completed: 20220303 Latest Revision: 20220303
رمز التحديث: 20240628
DOI: 10.1016/j.exger.2021.111686
PMID: 34995726
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-6815
DOI:10.1016/j.exger.2021.111686