دورية أكاديمية
Defining the minimal important change (MIC) and meaningful change value (MCV) for the Psoriatic Arthritis Disease Activity Score (PASDAS) in a routine practice cohort of patients with psoriatic arthritis.
| العنوان: | Defining the minimal important change (MIC) and meaningful change value (MCV) for the Psoriatic Arthritis Disease Activity Score (PASDAS) in a routine practice cohort of patients with psoriatic arthritis. |
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| المؤلفون: | Mulder MLM; Department of Rheumatology, Sint Maartenskliniek.; Department of Dermatology, Radboud University Medical Center., Bertram AM; Department of Rheumatology, Sint Maartenskliniek.; Department of Rheumatology Research, Sint Maartenskliniek, Nijmegen, The Netherlands., Wenink MH; Department of Rheumatology, Sint Maartenskliniek., Vriezekolk JE; Department of Rheumatology, Sint Maartenskliniek.; Department of Rheumatology Research, Sint Maartenskliniek, Nijmegen, The Netherlands. |
| المصدر: | Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2022 Oct 06; Vol. 61 (10), pp. 4119-4123. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Avenel, N.J. : Oxford University Press ; Distributed by Mercury International, c1999- |
| مواضيع طبية MeSH: | Arthritis, Psoriatic*/drug therapy, Cohort Studies ; Humans ; Severity of Illness Index |
| مستخلص: | Objective: The aim of the study was to determine the Minimal Important Change (MIC) values and Meaningful Change (MCV) values for the Psoriatic Arthritis Disease Activity Score (PASDAS) and the Standard Error of Measurement (s.e.m.) of the PASDAS. Methods: The routine practice data for 544 patients with PsA was available for analysis. An anchor-based method using linear regression analyses was used to determine the MICs and MCVs for the PASDAS. With this anchor-based method, we compared changes in the PASDAS score with an external reference (anchor). The anchor question inquired whether the patient's well-being had changed since their previous visit. It consisted of a 7-point Likert scale (range: very much improved to very much deteriorated). Interperiod correlation matrix analysis was performed to determine the s.e.m. Results: The overall MIC and MCV for the PASDAS were 0.67 (95% CI: 0.55, 0.79) and 1.34 (95% CI: 1.21, 1.46), respectively. Results for improvement and deterioration were 0.65 (95% CI: 0.46, 0.83) and 0.71 (95% CI: 0.49, 0.93) for the MIC, respectively, and 1.29 (95% CI: 1.11, 1.48) and 1.42 (95% CI: 1.19, 1.64) for the MCV, respectively. The s.e.m. was determined at 0.81. Conclusion: The MIC for the PASDAS is a tool for physicians treating patients with PsA enabling them to give context to the patient's perspective of disease activity, while the MCV might aid the use of the PASDAS in PsA clinical trials. (© The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.) |
| فهرسة مساهمة: | Keywords: Psoriatic Arthritis Disease Activity Score (PASDAS); meaningful change value (MCV); minimal important change (MIC); psoriatic arthritis |
| تواريخ الأحداث: | Date Created: 20220113 Date Completed: 20221010 Latest Revision: 20221017 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1093/rheumatology/keac025 |
| PMID: | 35025996 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1462-0332 |
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| DOI: | 10.1093/rheumatology/keac025 |