دورية أكاديمية
Diet Supplementation with Madagascar Cockroach Flour (Gromphadorhina portentosa) Improved Malnourished Mice Metabolism and Ameliorated Liver Inflammatory Markers.
| العنوان: | Diet Supplementation with Madagascar Cockroach Flour (Gromphadorhina portentosa) Improved Malnourished Mice Metabolism and Ameliorated Liver Inflammatory Markers. |
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| المؤلفون: | Oliveira JR; Laboratory of Health Science, Postgraduate Program in Health Sciences; Universidade Estadual de Montes Claros (UNIMONTES), Montes Claros, Minas Gerais,Brazil., Cota J; Institute of Agricultural Sciences (ICA), Universidade Federal de Minas Gerais (UFMG), Montes Claros, Minas Gerais,Brazil., Carvalho BM; Institute of Agricultural Sciences (ICA), Universidade Federal de Minas Gerais (UFMG), Montes Claros, Minas Gerais,Brazil., de Oliveira Costa T; Institute of Agricultural Sciences (ICA), Universidade Federal de Minas Gerais (UFMG), Montes Claros, Minas Gerais,Brazil., da Costa DV; Institute of Agricultural Sciences (ICA), Universidade Federal de Minas Gerais (UFMG), Montes Claros, Minas Gerais,Brazil., Santos SHS; Laboratory of Health Science, Postgraduate Program in Health Sciences; Universidade Estadual de Montes Claros (UNIMONTES), Montes Claros, Minas Gerais,Brazil. |
| المصدر: | Recent patents on food, nutrition & agriculture [Recent Pat Food Nutr Agric] 2021; Vol. 12 (2), pp. 112-122. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101526178 Publication Model: Print Cited Medium: Internet ISSN: 1876-1429 (Electronic) Linking ISSN: 18761429 NLM ISO Abbreviation: Recent Pat Food Nutr Agric Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sharjah : Bentham Science Publishers, 2009-2021. |
| مواضيع طبية MeSH: | Cockroaches* , Malnutrition*, Animals ; Diet ; Dietary Supplements ; Flour ; Liver ; Madagascar ; Male ; Mice ; Patents as Topic |
| مستخلص: | Background: Malnutrition and accessible high-quality protein food sources are two of the world's alimentary challenges. Edible insects are nowadays recognized as a possible functional food solution with lower environmental impacts and beneficial health effects. Objective: In this context, the aim of the present study is to evaluate Madagascar cockroach (Gromphadorhina portentosa) flour supplementation effects on a malnourished mice model, considering its effects on metabolism, adiposity, and inflammatory liver profiles. Method: Male Swiss mice are divided into five groups and fed with experimental diets for eight weeks, including a standard diet (ST) ad libitum, AIN93 ad libitum (AIN), insect flour-enriched AIN93 (AIN+IM), AIN-40% feed restriction (AIN-FR), and insect flour-enriched AIN-40% of feed restriction (AIN-FR+IM). The metabolic profiles, adipose tissue, biochemical parameters, and liver IL-6 and IL-10 expression are evaluated. Results: The main findings show a body weight and metabolism improvement followed by an increased recovery of the adipocyte area in the AIN-FR+IM group when compared to the AIN-FR malnourished group. Reduced hepatic IL-6 and increased IL-10 expression are also detected in the AIN-FR+IM group. Conclusion: The results show that insect flour supplementation enhances both body weight and adiposity gain/recovery. The results also show hepatic improvement of inflammatory markers. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| فهرسة مساهمة: | Keywords: Gromphadorhina portentosa; Madagascar cockroach flour; edible insects; human diseases animal model; liver inflammation; malnutrition; protein alternative diet |
| تواريخ الأحداث: | Date Created: 20220114 Date Completed: 20220117 Latest Revision: 20220117 |
| رمز التحديث: | 20240628 |
| DOI: | 10.2174/2772574X12666211210160819 |
| PMID: | 35026975 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1876-1429 |
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| DOI: | 10.2174/2772574X12666211210160819 |