دورية أكاديمية
An Integrative Sialomic Analysis Reveals Molecules From Triatoma sordida (Hemiptera: Reduviidae).
| العنوان: | An Integrative Sialomic Analysis Reveals Molecules From Triatoma sordida (Hemiptera: Reduviidae). |
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| المؤلفون: | Praça YR; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil.; Programa Pós-Graduação em Ciências Médicas, Faculty of Medicine, University of Brasilia, Brasilia, Brazil., Santiago PB; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., Charneau S; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., Mandacaru SC; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., Bastos IMD; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., Bentes KLDS; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil.; Programa Pós-Graduação em Ciências Médicas, Faculty of Medicine, University of Brasilia, Brasilia, Brazil., Silva SMM; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., da Silva WMC; Federal Institute of Goiás, Formosa, Brazil., da Silva IG; Department of Parasitology, Federal University of Goiás, Goiânia, Brazil., de Sousa MV; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, University of Brasilia, Brasilia, Brazil., Soares CMA; Laboratório de Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil., Ribeiro JMC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD, United States., Santana JM; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil.; Programa Pós-Graduação em Ciências Médicas, Faculty of Medicine, University of Brasilia, Brasilia, Brazil., de Araújo CN; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia, Brazil.; Programa Pós-Graduação em Ciências Médicas, Faculty of Medicine, University of Brasilia, Brasilia, Brazil.; Faculty of Ceilândia, University of Brasilia, Brasilia, Brazil. |
| المصدر: | Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Jan 03; Vol. 11, pp. 798924. Date of Electronic Publication: 2022 Jan 03 (Print Publication: 2021). |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Media SA |
| مواضيع طبية MeSH: | Triatoma*/genetics , Triatominae*, Animals ; Chromatography, Liquid ; Humans ; Insect Vectors ; Tandem Mass Spectrometry |
| مستخلص: | Triatomines have evolved salivary glands that produce versatile molecules with various biological functions, including those leading their interactions with vertebrate hosts' hemostatic and immunological systems. Here, using high-throughput transcriptomics and proteomics, we report the first sialome study on the synanthropic triatomine Triatoma sordida . As a result, 57,645,372 reads were assembled into 26,670 coding sequences (CDS). From these, a total of 16,683 were successfully annotated. The sialotranscriptomic profile shows Lipocalin as the most abundant protein family within putative secreted transcripts. Trialysins and Kazal-type protease inhibitors have high transcript levels followed by ubiquitous protein families and enzyme classes. Interestingly, abundant trialysin and Kazal-type members are highlighted in this triatomine sialotranscriptome. Furthermore, we identified 132 proteins in T. sordida salivary gland soluble extract through LC-MS/MS spectrometry. Lipocalins, Hemiptera specific families, CRISP/Antigen-5 and Kazal-type protein inhibitors proteins were identified. Our study provides a comprehensive description of the transcript and protein compositions of the salivary glands of T. sordida . It significantly enhances the information in the Triatominae sialome databanks reported so far, improving the understanding of the vector's biology, the hematophagous behaviour, and the Triatominae subfamily's evolution. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Praça, Santiago, Charneau, Mandacaru, Bastos, Bentes, Silva, da Silva, da Silva, de Sousa, Soares, Ribeiro, Santana and de Araújo.) |
| References: | Biochimie. 2006 Jun;88(6):673-81. (PMID: 16469426) J Trop Med. 2012;2012:705326. (PMID: 22523500) Insect Biochem Mol Biol. 2002 Sep;32(9):991-7. (PMID: 12213235) Bioinformatics. 2009 May 1;25(9):1189-91. (PMID: 19151095) Biochemistry. 2006 Feb 14;45(6):1765-74. (PMID: 16460023) Toxins (Basel). 2016 Sep 29;8(10):. (PMID: 27690102) J Venom Anim Toxins Incl Trop Dis. 2021 Mar 08;27:e20200098. (PMID: 33747067) Bioinformatics. 2012 Dec 1;28(23):3150-2. (PMID: 23060610) PLoS Negl Trop Dis. 2016 Apr 29;10(4):e0004581. (PMID: 27129103) Front Cell Infect Microbiol. 2020 Sep 02;10:459. (PMID: 32984079) J Biol Chem. 2010 Dec 10;285(50):39001-12. (PMID: 20889972) Bioinformatics. 2006 Jul 1;22(13):1658-9. (PMID: 16731699) Mol Biol Evol. 2018 Jun 1;35(6):1547-1549. (PMID: 29722887) Acta Trop. 2020 Oct;210:105473. (PMID: 32505596) Curr Allergy Asthma Rep. 2020 Jul 9;20(10):58. (PMID: 32647993) Mem Inst Oswaldo Cruz. 1999 May-Jun;94(3):347-51. (PMID: 10348981) Infect Genet Evol. 2010 Mar;10(2):184-91. (PMID: 19900580) Nucleic Acids Res. 2020 Jan 8;48(D1):D265-D268. (PMID: 31777944) Biochem J. 2006 Jun 15;396(3):509-15. (PMID: 16542158) FEBS J. 2008 Mar;275(5):994-1002. (PMID: 18221493) BMC Bioinformatics. 2003 Sep 11;4:41. (PMID: 12969510) Nucleic Acids Res. 1999 Jan 1;27(1):229-32. (PMID: 9847187) Insect Mol Biol. 2002 Dec;11(6):585-93. (PMID: 12421416) Endocr Rev. 2008 Dec;29(7):865-97. (PMID: 18824526) Infect Agents Dis. 1995 Sep;4(3):143-52. (PMID: 8548192) J Med Entomol. 2012 May;49(3):563-72. (PMID: 22679863) Br J Math Stat Psychol. 2019 Feb;72(1):136-154. (PMID: 30468259) Nat Biotechnol. 2011 May 15;29(7):644-52. (PMID: 21572440) Mol Cell Proteomics. 2017 Apr;16(4):552-566. (PMID: 28130397) Biochim Biophys Acta. 2000 Oct 18;1482(1-2):9-24. (PMID: 11058743) Insect Biochem Mol Biol. 2004 Sep;34(9):971-9. (PMID: 15350616) J Biol Chem. 2013 May 17;288(20):14341-14361. (PMID: 23564450) J Proteomics. 2017 Jun 6;162:30-39. (PMID: 28442446) Nat Commun. 2018 Feb 22;9(1):755. (PMID: 29472578) Bioinformatics. 2014 Aug 1;30(15):2114-20. (PMID: 24695404) J Exp Biol. 2006 Jan;209(Pt 2):343-52. (PMID: 16391356) J Biol Chem. 2005 Apr 1;280(13):12316-29. (PMID: 15677462) Nat Methods. 2011 Sep 29;8(10):785-6. (PMID: 21959131) J Proteomics. 2011 Aug 24;74(9):1693-700. (PMID: 21601023) Int J Parasitol. 2007 Oct;37(12):1351-8. (PMID: 17575982) Science. 2015 Mar 6;347(6226):1066-7. (PMID: 25745146) Methods Enzymol. 1994;235:657-67. (PMID: 7520121) Nat Genet. 2000 May;25(1):25-9. (PMID: 10802651) J Lipid Res. 2007 Mar;48(3):489-502. (PMID: 17148551) Blood Rev. 2011 Jul;25(4):155-67. (PMID: 21496978) Toxins (Basel). 2016 Feb 15;8(2):44. (PMID: 26891325) Nucleic Acids Res. 2009 Jan;37(Database issue):D205-10. (PMID: 18984618) Int Arch Allergy Immunol. 2000 Oct;123(2):99-106. (PMID: 11060481) Biochem Biophys Res Commun. 2003 Jun 13;305(4):869-75. (PMID: 12767911) Sci Rep. 2017 Mar 16;7:44593. (PMID: 28300174) Front Cell Infect Microbiol. 2018 Nov 16;8:405. (PMID: 30505806) Insect Biochem Mol Biol. 2008 Feb;38(2):213-32. (PMID: 18207082) PLoS Negl Trop Dis. 2014 Dec 04;8(12):e3372. (PMID: 25474469) Ecol Evol. 2020 Aug 17;10(18):9932-9947. (PMID: 33005355) Nat Protoc. 2016 Jan;11(1):102-17. (PMID: 26658470) Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11845-50. (PMID: 9342325) J Med Entomol. 2015 May;52(3):351-8. (PMID: 26334808) Acta Trop. 2009 May-Jun;110(2-3):88-100. (PMID: 19385053) Am J Trop Med Hyg. 2012 Jun;86(6):1005-14. (PMID: 22665609) Nucleic Acids Res. 2014 Jan;42(Database issue):D222-30. (PMID: 24288371) Exp Parasitol. 2011 Dec;129(4):362-7. (PMID: 21963772) Insect Biochem Mol Biol. 2004 Jan;34(1):61-79. (PMID: 14976983) J Biol Chem. 1993 Aug 5;268(22):16216-22. (PMID: 8344906) Rev Saude Publica. 1980 Sep;14(3):265-99. (PMID: 7015472) Insect Biochem Mol Biol. 2001 Mar 15;31(4-5):465-72. (PMID: 11222956) Insect Biochem Mol Biol. 2007 Jul;37(7):702-12. (PMID: 17550826) J Allergy Clin Immunol. 1993 Nov;92(5):707-16. (PMID: 8227862) Mol Microbiol. 1991 Mar;5(3):521-8. (PMID: 2046545) J Med Entomol. 1998 Jul;35(4):599-610. (PMID: 9701952) Nucleic Acids Res. 2019 Jan 8;47(D1):D442-D450. (PMID: 30395289) Rev Panam Salud Publica. 1998 Jan;3(1):21-5. (PMID: 9503959) J Proteome Res. 2011 Feb 4;10(2):669-79. (PMID: 21058630) Acta Trop. 2017 Oct;174:122-129. (PMID: 28690145) Nat Methods. 2008 Jul;5(7):621-8. (PMID: 18516045) Acta Trop. 2020 Dec;212:105679. (PMID: 32860747) Front Biosci (Landmark Ed). 2009 Jan 01;14:2051-88. (PMID: 19273185) Annu Rev Biochem. 1992;61:87-111. (PMID: 1497325) Rev Saude Publica. 1978 Sep;12(3):291-6. (PMID: 108799) BMC Bioinformatics. 2004 Aug 19;5:113. (PMID: 15318951) J Biol Chem. 2002 Feb 22;277(8):6207-13. (PMID: 11751887) Dev Comp Immunol. 2010 Apr;34(4):377-86. (PMID: 19995574) J Proteomics. 2018 Mar 1;174:47-60. (PMID: 29288089) Trop Med Int Health. 1998 May;3(5):364-72. (PMID: 9623941) Parasit Vectors. 2017 Feb 13;10(1):79. (PMID: 28193252) Trends Parasitol. 2020 Mar;36(3):250-265. (PMID: 32007395) Toxins (Basel). 2019 Nov 18;11(11):. (PMID: 31752210) PLoS Biol. 2010 Nov 30;8(11):e1000547. (PMID: 21152418) Nucleic Acids Res. 1997 Sep 1;25(17):3389-402. (PMID: 9254694) J Biol Chem. 1995 Dec 1;270(48):28629-34. (PMID: 7499380) Parasit Vectors. 2015 Sep 29;8:495. (PMID: 26419232) Insect Biochem Mol Biol. 2004 Oct;34(10):1051-8. (PMID: 15475299) Insect Biochem Mol Biol. 2004 Oct;34(10):1011-23. (PMID: 15475296) PLoS Negl Trop Dis. 2018 Feb 20;12(2):e0006243. (PMID: 29462134) Adv Parasitol. 2018;99:265-344. (PMID: 29530308) Toxicon. 2010 Dec 15;56(7):1120-9. (PMID: 19925819) Curr Top Microbiol Immunol. 2001;257:85-111. (PMID: 11417123) Mem Inst Oswaldo Cruz. 1999 Jul-Aug;94(4):451-7. (PMID: 10446000) Rev Inst Med Trop Sao Paulo. 2009 Sep-Oct;51(5):247-53. (PMID: 19893976) J Biomed Biotechnol. 2010;2010:641025. (PMID: 20976270) |
| معلومات مُعتمدة: | Z01 AI000810 United States ImNIH Intramural NIH HHS |
| فهرسة مساهمة: | Keywords: blood-feeding; salivary glands; salivary molecules; sialome; sialoproteome; sialotranscriptome; triatomine |
| تواريخ الأحداث: | Date Created: 20220120 Date Completed: 20220128 Latest Revision: 20220128 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8762107 |
| DOI: | 10.3389/fcimb.2021.798924 |
| PMID: | 35047420 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2235-2988 |
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| DOI: | 10.3389/fcimb.2021.798924 |