التفاصيل البيبلوغرافية
| العنوان: |
Why are Polish women diagnosed with invasive cervical cancer after negative cytology in the organized screening programme - a pilot reevaluation of negative Pap smears preceding diagnoses of interval cancers. |
| المؤلفون: |
Komerska K; Department of Cancer Prevention, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Macios A; Department of Cancer Prevention, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Glińska P; Warsaw PhD School in Natural and BioMedical Sciences, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland., Olszewski W; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland., Didkowska J; Polish National Cancer Registry, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland., Wojciechowska U; Polish National Cancer Registry, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland., Kamiński MF; Department of Cancer Prevention, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Nowakowski A; Department of Cancer Prevention, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. |
| المصدر: |
Polish journal of pathology : official journal of the Polish Society of Pathologists [Pol J Pathol] 2021; Vol. 72 (3), pp. 261-266. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Polish Society Of Pathologists Country of Publication: Poland NLM ID: 9437432 Publication Model: Print Cited Medium: Print ISSN: 1233-9687 (Print) Linking ISSN: 12339687 NLM ISO Abbreviation: Pol J Pathol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Kraków : Polish Society Of Pathologists, 1994- |
| مواضيع طبية MeSH: |
Uterine Cervical Neoplasms*/diagnosis, Early Detection of Cancer ; Female ; Humans ; Papanicolaou Test ; Pilot Projects ; Poland/epidemiology |
| مستخلص: |
We have aimed to study reasons for reporting false-negative cytology results preceding diagnosis of interval cervical cancers (CC) in Poland. Data on all Pap smears collected in the organised screening in 2010-2015 were retrieved from the electronic database and linked with Polish National Cancer Registry (PNCR) data. False-negative results were defined as those sampled and assessed normal up to 3.5 years before diagnosis of invasive CC. False-negative slides were then seeded among twice as many randomly selected slides from the same lab and reviewed independently by three expert cytomorphologists. New diagnosis was established when experts agreed on a result. Of 48 selected false-negative slides, 1 case was diagnosed as a low-grade abnormality, 22 cases as a high-grade abnormalities, 3 cases as unsatisfactory for evaluation and 5 as no intraepithelial lesion of malignancy (NILM) by all three experts. There was no agreement in 17 cases. Percentages of agreement between experts was 64.6. Interobserver agreement rate was moderate with Fleiss' κ values. Our pilot study indicates evaluation errors as the main reason of false-negative cytology preceding interval CC in the organized screening programme in Poland. True lack of abnormal cells on the slide is the next reason. |
| فهرسة مساهمة: |
Keywords: cervical cancer; cervical cancer screening; interval cancer; cytology |
| تواريخ الأحداث: |
Date Created: 20220120 Date Completed: 20220121 Latest Revision: 20220121 |
| رمز التحديث: |
20231215 |
| DOI: |
10.5114/pjp.2021.112832 |
| PMID: |
35048639 |
| قاعدة البيانات: |
MEDLINE |
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