دورية أكاديمية
Molecular basis and clinical perspectives of deep brain stimulation for major depressive disorder.
| العنوان: | Molecular basis and clinical perspectives of deep brain stimulation for major depressive disorder. |
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| المؤلفون: | Teixeira SA; Hospital Geral de Fortaleza - HGF, Fortaleza, Ceará, Brazil., Moreira JLS; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Sousa NRT; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Pereira AMC; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Rodrigues PN; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Santos ASD; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Andrade AMLC; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Rolim Neto ML; Juazeiro do Norte School of Medicine from Juazeiro do Norte - FMJ/Estacio, Juazeiro do Norte, Ceará, Brazil., Araújo JEB; School of Medicine, Federal University of Campina Grande - UFCG, Cajazeiras, Paraíba, Brasil., Machado SSF; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Vieira NB; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Lima DGS; Juazeiro do Norte School of Medicine from Juazeiro do Norte - FMJ/Estacio, Juazeiro do Norte, Ceará, Brazil., Filho FHP; School of Medicine - Universidad Central del Paraguay - Sede 2 - Asunción, Paraguay. |
| المصدر: | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 Apr; Vol. 42 (4), pp. 683-685. Date of Electronic Publication: 2022 Jan 20. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Thousand Oaks, CA : SAGE Publications Original Publication: New York : Raven Press, c1981- |
| مواضيع طبية MeSH: | Deep Brain Stimulation*/methods , Depressive Disorder, Major*/diagnostic imaging , Depressive Disorder, Major*/pathology , Depressive Disorder, Major*/therapy , Depressive Disorder, Treatment-Resistant*/diagnostic imaging , Depressive Disorder, Treatment-Resistant*/pathology , Depressive Disorder, Treatment-Resistant*/therapy, Gyrus Cinguli/physiology ; Humans ; Positron Emission Tomography Computed Tomography |
| مستخلص: | It is possible to consider the stimulation of the cingulate gyrus in its portion below the corpus callosum (SCC, or subcallosal cingulate cortex) as an effective, promising, and safe alternative intervention for treatment-resistant depression. In studies with deep brain stimulation - DBS, when follow-on with functional magnetic resonance imaging and/or PET-CT (Positron emission tomography-computed tomography) is performed, it is observed an increase in the blood supply and glucose metabolism in this region, which is the anterior part of the limbic system. This same location has good experimental results also for the treatment of anorexia nervosa. The hypotheses suggest a greater activation of the reward system, a greater sense of well-being, and a consequent reduction in depressive symptoms, the objective of the treatment. Over the last 20 years, multicenter studies have shown symptomatic improvement in 50-60% of patients, and about a third even reach criteria for remission of the depressive disorder. |
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| فهرسة مساهمة: | Keywords: Major depressive disorder – MDD; deep brain stimulation – DBS; neuro-psychiatry; neurosurgical procedures; positron emission tomography–computed tomography – PET-CT |
| تواريخ الأحداث: | Date Created: 20220120 Date Completed: 20220425 Latest Revision: 20230121 |
| رمز التحديث: | 20230123 |
| مُعرف محوري في PubMed: | PMC9051149 |
| DOI: | 10.1177/0271678X221074279 |
| PMID: | 35048722 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1559-7016 |
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| DOI: | 10.1177/0271678X221074279 |